Acute Encephalitis: Diagnosis and Management

Acute Encephalitis: Diagnosis and Management
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This talk delves into diagnosing and managing acute encephalitis, focusing on infectious causes and featuring clinical vignettes. Discussions cover various etiologies globally, highlighting the role of encephalitis as a sentinel syndrome for emerging infections.

  • Encephalitis
  • Diagnosis
  • Management
  • Neurology
  • Infections

Uploaded on Mar 11, 2025 | 0 Views


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  1. WORLD CONGRESS OF NEUROLOGY Infections 2 Teaching Session Encephalitis Tuesday 17thOctober 2023 Montr al, Canada Dr Nicholas Davies Consultant Neurologist, Chelsea & Westminster and Charing Cross Hospitals, London, UK nicholas.davies12@nhs.net

  2. Disclosures: Dr Davies has no financial disclosures. Dr Davies is chair of the Encephalitis Society s Scientific Advisory Panel.

  3. Session Description: This talk explores the diagnosis and acute management of persons suffering acute encephalitis. It will be illustrated with clinical vignettes. Whilst encephalitis can result from multiple pathogenetic processes the primary focus will be infectious causes of encephalitis; however, brief discussion of autoimmune encephalitis following herpes simplex encephalitis will be covered. Discussed aetiologies of encephalitis will be world-focussed covering both sporadic and epidemic causes, recognising that encephalitis can be a sentinel syndrome for emerging infections.

  4. Learning Objectives: 1. Acute infectious encephalitis is often a syndrome amenable to anti-microbial therapy, which if instituted promptly improves outcome. 2. Molecular techniques and newer serological assays have improved diagnostic sensitivity. 3. Acute encephalitis may be a sentinel syndrome for emerging infections. 4. Some forms of acute encephalitis are preventable by public health measures.

  5. References: Venkatesan et al (2019) Acute encephalitis in immunocompetent adults. Lancet 16: 702-716. Tyler KL. (2018) Acute Viral Encephalitis. N Engl J Med. 379: 557-566. Dalmau J, Graus F. (2018) Antibody-Mediated Encephalitis. N Engl J Med. 378: 840-851. Solomon, T., Michael, B.D., Smith, P.E., et al. (2012) Management of suspected viral encephalitis in adults - Association of British Neurologists and British Infection Association National Guidelines. Journal of Infection 64, 347-373. Davies N & Thwaites G (2011) Infections of the nervous system. Practical Neurology; 11:121-131.

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