Allergic Bronchial Asthma
Learn about allergic bronchial asthma, its history, characteristics, prevalence, genetic and environmental factors, immunological aspects, symptoms, diagnosis methods, and treatment options. Explore the impact of this condition on individuals and the global population.
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Asma bronquial alrgica UNIVERSIDAD AUT NOMA DE SINALOA ASMA BRONQUIAL AL RGICA JAVIER ACOSTA ALVAREZ MSP. MAR A GUADALUPE RAMIREZ ZEPEDA
Asma bronquial alrgica En 1902, Richet y Portier, inyectaron perros con extractos de an monas y describieron un tipo particular de reacci n sist mica a la cual le dieron el nombre de anafilaxis. En 1906 Von Pirquet emple el t rmino alergia para designar una respuesta alterada de un organismo al ser expuesto a substancias del medio ambiente.
Asma bronquial alrgica Proceso al rgico caracterizado por periodos intermitentes y reversibles de obstrucci n bronquial, acompa ados de inflamaci n e hiperreactividad.
Asma bronquial alrgica Predomina en ni os de 5 a 12 a os. La incidencia fluct a entre un 5 a un 20% de la poblaci n mundial. 300 millones de personas en el mundo padecen asma.
Asma bronquial alrgica Los factores mas importantes son: Gen ticos: genes ADAM33, Ph1-SETDB2, DPP10, GPRA, PTGDR. Ambientales. Infeccioso.
Asma bronquial alrgica IL-2 IL-4 IL-12 IL-5 Eos Th2 CD4 http://upload.wikimedia.org/wikipedia/commons/b/bf/Dendritic_cell.png IL-4 LB Ig-E
Asma bronquial alrgica Permeabilidad capilar Histamina Heparina Leucotrienos IL TNF- Contracci n de musculatura lisa Hipersecreci n
Asma bronquial alrgica + Vasodilataci n + Espasmo muscular +Eosin filos +Macr fagos Quimioquinas Citoquinas
Asma bronquial alrgica TGF- Fibrosis Eos
Asma bronquial alrgica Espirometr a Prueba cut nea. Recuento de eosin filos Dosificaci n de Ig-E Determinaci n de Ig-E espec fica Identificaci n y cuantificaci n de al rgenos. Radiograf a de t rax Electrocardiograma (ECG)
Asma bronquial alrgica Broncodilatadores Antiinflamatorios Modificadores de Lcts Aminofilina-teofilina AcsMcs contra receptor de la Ig-E
Asma bronquial alrgica 1. Educaci n 2. Manejo: A. Evitar factores desencadenantes B. Uso de inhaladores - agonistas C. Usar esteroides inhalados 2 veces al d a.
