Ambiguous Genitalia
Explore the complexities of ambiguous external genitalia, hermaphroditism, and management of Congenital Adrenal Hyperplasia (CAH) through counseling, hormone replacement, surgical correction, and follow-up care. Addressing growth, development, and psychological aspects in individuals with CAH is crucial for holistic treatment.
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Presentation Transcript
Ambiguous External Genitalia Male Female 46XY Testis receptor 5a-receptor 46XX Androgen excess True hermaphrodite
1. 2. 3. Na / K 17-KS Androgen / AMH 17-OHP
Treat : CAH Strong support / psychologic preparation / counseling : Natural Hx / Dx / management Growth development, bone age Reproduction: anovulation, hirsutism Multidisciplinary Hormone replacement (Steroids) Adrenal crisis Hydrocortisone, fludrocortisones long-acting : prednisone, dexamethasone Monitor :17-OHP (500-4,000 ng/ml) Surgical correction Follow-up (health, height, psychosocial)
