Ancillary Studies Committee Updates September 2017
Discover the latest updates from the Ancillary Studies Committee in September 2017. This includes the approval of new proposals covering a range of topics such as cardiovascular diseases, Alzheimer's disease, lung disorders, and more. Explore the funded ancillary studies and proposed research projects beyond Exam 6, offering insights into various health conditions and advancements in medical research.
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Presentation Transcript
ANCILLARY STUDIES COMMITTEE September 2017
5 months of activity Apr 2017 Aug 2017 11 new proposals reviewed and approved by SC
ANCILLARY STUDIES COMMITTEE September 2017 New proposals, SC approved: A333 Bourfiss (Bluemke) Right precordial T-wave inversion and heart position in the thorax; arrhythmogenic R ventricular cardiomyopathy A334 Hughes (Burke) Multisite study of vascular contributions to Alzheimer s disease A335 Chamberlain (Budoff) Automated CAC scoring in gated cardiac and ungated lung CT scans A336 Barr Personalized risk estimation for ventilatory and emphysematous endophenotypes in chronic lung dz A337 Thomas (Criqui) Thoracic aorta and carotid artery calcium on chest CT
ANCILLARY STUDIES COMMITTEE September 2017 New proposals, SC approved: A338 Funk (K. Liu, Kaufman) Air pollution, oxidative stress and early CVD phenotypes A339 Allison Subclavian artery calcification A340 Zghaib (Lima) Podocyturia mRNAs and prediction of adverse CV outcomes A341 Rotter NIH Data Commons; large-scale biomedical data A342 Al Aref (Budoff) Prediction of major CV events using clinical characteristics and CV imaging; machine learning A343 Budoff Bone density
ANCILLARY STUDIES COMMITTEE Funded Exam 6 Ancillary Studies: Bertoni/Shah All FCs All FCs All FCs From risk factors to early heart failure Atrial fibrillation burden, vascular disease of brain Pulmonary vascular perfusion Heckbert Barr Smith, B. Kramer All FCs All FCs COPD in non-smokers Urinary KNOWledge Study Individual response to Vitamin D (INVITE trial) Kestenbaum WF, Col, JH, NW WF, Col, JH, Minn WF, JH Liu Epigenetics of atherosclerosis (carotid ultrasound) Ding Epigenetics of cognitive function WF, Col, JH, Minn Col Liu, Ding Epigenetics of T2D (blood draw) Shea HDL-mediated cholesterol efflux & carotid FDG PET Hughes/Craft WFU Vascular contributions to Alzheimer s (Memory) Wang NW Tissue sodium, inflammation, BP
ANCILLARY STUDIES COMMITTEE Funded Ancillary Studies with Visits Beyond Exam 6 Heckbert All FCs Atrial fibrillation burden, vascular disease of brain brain MRI Proposed Ancillary Studies with Visits Beyond Exam 6 Hughes All FCs Multisite Alzheimer s Dementia Study 1: cog testing,MRI,PET 2: cog testing,MRI
ANCILLARY STUDIES COMMITTEE September 2017 All Ancillary studies N (%) Proposals 346 (100) Withdrawn 72 (21) Funding pending 91 (26) Funded/active 131 (38) Completed 52 (15)
ANCILLARY STUDIES COMMITTEE September 2017 Committee members Matt Allison Sue Bielinski Chris Delaney Phil Greenland Susan Heckbert Nels Olson Ben Smith Pothur Srinavas Coordinator: Sandi Shrager
