Bioinformatics: Types of Sequence Alignment
Explore the various types of sequence alignment including pairwise alignment, substitution, insertion, deletion, and alignment of multiple sequences. Understand the concept of matching, mismatches, and gaps in bioinformatics alignment processes. Images provided for better visualization.
Download Presentation
Please find below an Image/Link to download the presentation.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author. If you encounter any issues during the download, it is possible that the publisher has removed the file from their server.
You are allowed to download the files provided on this website for personal or commercial use, subject to the condition that they are used lawfully. All files are the property of their respective owners.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author.
E N D
Presentation Transcript
1 UNIVERSITY OF BASRAH / COLLEGE OF SCIENCE Bioinformatics 1 Types ofAlignment 2 Pairwise Sequence Alignment Prof.Dr. Saad S. Mahdi Al-Amara LECTURE PhD. 5
2 Sequence Alignment Types ofAlignment 1. Pairwise Sequence Alignment Apairwise alignment consists of a series of paired bases, one base from each sequence.There are three types of pairs: (1) matches = the same nucleotide appears in both sequences. (2) mismatches = different nucleotides are found in the two sequences. (3) gaps = a base in one sequence and a null base in the other .
3 SequenceAlignment Substitution: replacement of one base by another AAGA AACA Insertion: addition of bases into the sequence AAGA AATGA Deletion: subtraction of bases from the sequence AAGA AGA
4 SequenceAlignment Alignment of two (pairwise) or more (multiple) sequences is performed by identifying overlapping regions and positioning parallel positions one against the other
5 SequenceAlignment
6 SequenceAlignment
7 SequenceAlignment
8 SequenceAlignment
