Building the Next-Gen Life Sciences Supply Chain

Clinical and Commercial Supply Chain Steering Committee Meeting October 27, 2022 GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCI!ENCES IN THE WAKE OF COVID 19 PANDEMIC Welcome !

Clinical and Commercial Supply Chain Steering Committee Meeting October 27, 2022 Agenda GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCIENCES IN THE WAKE OF COVID 19 PANDEMIC Collaboration Platform Announcement Work Stream Updates Workshop Suggestions for 2023 BSMA Annual Conference (March 8 & 9) Open Forum (if time permits) Next Meeting Introductions (Name and Company)

Clinical and Commercial Supply Chain Steering Committee Meeting October 27, 2022 EnterAkt GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCIENCES IN THE WAKE OF COVID 19 PANDEMIC communicate, coordinate, and collaborate Capabilities include the ability to Create posts with multimedia content Archive video meetings (including webinars and podcasts) Look up information based on each user s stated interests (e.g. S&OP, IRT, Analytics) Create private groups (e.g. Steering Committees) and sub-groups (e.g. Workstreams) for collaborating and disseminating information Target Launch Date: Early December Collaboration platform that allows participants to effectively and efficiently

Clinical and Commercial Supply Chain Steering Committee Meeting October 27, 2022 Work Stream Update Clinical Supply & Demand Planning Co-Chairs: Ryan Mills (Denali) and Sebastien Coppe (N-Side) GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCIENCES IN THE WAKE OF COVID 19 PANDEMIC Pedroni (Eikon), Malou Berdan (Beigene), Derek Thornton (Amgen), Hana Raap (Amgen), JP Kappelle (4G), Allen Jacque (Kinaxis), Scott Sabalvaro (Pliant Therapeutics), Gerry McKenna (Catalent), Melissa Lucas) (BIOCOM) Advisors: Luke Moyer (Incyte), Brittney Elko (Tricida), Jon Miller (Wugen), Antonio Tramontano (Novartis), Ryan Scope (draft): Demand Planning, Supply Planning, S&OP, Inventory Optimization. More details to follow. Topic and timing for first webinar: Introduction to Planning (timing tbd) Questions or comments?

Clinical and Commercial Supply Chain Steering Committee Meeting October 27, 2022 Work Stream Update Moving Beyond Excel and Point Solutions Co-Chairs: Rutesh Desai (Beigene) and Dan Silva (Tenthpin) Advisors: Ryan Pedroni (Eikon), Allen Jacque (Kinaxis), Antonio Tramontano (Novartis), Yogendra Chordia (Schrocken), Bob Lamont (Clarkston), Catherine Hall (Endpoint Clinical), Ewan Pumford (Catalent), Melissa Lucas (BIOCOM) GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCIENCES IN THE WAKE OF COVID 19 PANDEMIC Scope: Why? When? Options? Cost? What is needed to start? (See additional information on next slide) Timing and topic for first webinars: Early December, Early February, March 9 (Annual Conference). Topic for first webinar will reflect lessons learned from clients who are in the early stages of an ERP implementation Questions or comments?

Work Stream: Moving Beyond Excel and Point Solutions What to avoid? When? What is needed to start? What will it cost? Why? What to do first? Other Leading Industry Tools What are the options?

Work Stream: Moving Beyond Excel and Point Solutions Our Path Forward: 2022 2023 D O N J F M A Client example(s) Webinar #2 BSMA Annual Event Panel Discussion Client example(s) Webinar #1 Our Kickoff! Internal Internal workstream leads meeting workstream leads meeting Internal Internal workstream leads meeting workstream leads meeting

Work Stream: Moving Beyond Excel and Point Solutions Notes from first meeting (October 20, 2022): Focused on the key questions that need to be addressed for our audience. In addition to the questions listed on previous slide, here are some other comments made while reviewing the slide What is the level of experience in the audience? What is the impact on change management? What are the potential symptoms that can identify the need for moving to an ERP solution? What is the value to the business and the company? What are the key milestones that need to be prioritized for the ERP journey? We should get a couple of companies at either end of their systems lifecycle to share their story. Antonio from Novartis will be sharing a story about their Digital Revolution for one of the sessions. We are still looking at another company who are in the early phase of their ERP lifecycle to share their perspective. Data is the backbone of any implementation, and this forum thinks it is an essential part of any ERP implementation.

Clinical and Commercial Supply Chain Steering Committee Meeting October 27, 2022 Work Stream Update Transitioning from Clinical to Commercial: Ensuring a Successful Product Launch Co-Chairs: Mike Dallman (Avidity BioScience) and Aparna Seksaria (SAP) Advisors: Allen Jacque (Kinaxis), Bob Lamont (Clarkston), Yogendra Chordia (Schrocken), Ann McMahon (Catalent), Melissa Lucas (BIOCOM), Paul Seaback (Dermavant), Marc Trombella (BioMarin) GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCIENCES IN THE WAKE OF COVID 19 PANDEMIC Scope (draft): Processes, Organizational structure, People & culture, CMO selection, Batch sizes, Managing process changes, Regulatory challenges, Logistics Topic and timing for first webinar: Questions and comments?

Clinical and Commercial Supply Chain Steering Committee Meeting October 27, 2022 Proposed Workshop Topics for Annual Conference (Morning of March 8, 2023 in Foster City, CA) 1 or 2 half-day sessions GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCIENCES IN THE WAKE OF COVID 19 PANDEMIC How to optimize your clinical studies using IRT How to apply analytics to achieve a successful clinical study Understanding and Adherence to Clinical Supply Compliance Regulations Direct-to-Patient and JIT Challenges & Solutions Budgeting and Managing Clinical Supply Expenses Comparators and Ancillary Supplies Best Practices

Clinical and Commercial Supply Chain Steering Committee Meeting October 27, 2022 Next Meeting: Thursday, December 8 8 am PT or 9 am PT? GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCIENCES IN Ba

Clinical and Commercial Supply Chain Steering Committee Meeting October 27, 2022 Open Forum What challenges or topics would you like to discuss? Supply shortages? Hiring and staffing? GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCIENCES IN Ba New regulations? Other?

Clinical and Commercial Supply Chain Steering Committee Meeting October 27, 2022 Back-Up Slides GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCIENCES IN Ba

Clinical and Commercial Supply Chain Steering Committee Steering Committee Charter Educate BSMA community on current and future state of clinical and commercial supply chain to promote industry standardization GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCIENCES IN THE WAKE OF COVID 19 PANDEMIC providers can incorporate into their design Share at BSMA webinars & conferences Identify, discuss and align to industry best practices that members and solution Includes input from virtual, small and medium size members Improve connectivity with internal and external customers and suppliers, and hand offs between clinical and commercial Understand cost drivers and enable members to measure and manage these in meaningful segments Help members educate their executives around the need and value of ERP solutions, and what technologies are available Enable people to connect with their peers

Clinical and Commercial Supply Chain Steering Committee Meeting Steering Committee Website Includes steering committee mission, members, meeting slides and recordings, webinar content and recordings GLOBAL LEADERS ADDRESS BUILDING THE NEXT GEN SUPPLY CHAIN OF LIFE SCIENCES IN THE WAKE OF COVID 19 PANDEMIC Clinical & Commercial Supply Chain Steering Committee - BSMA (biosupplyalliance.com)