Carbonyl Condensation Reactions and Aldol Products
Learn about the reactivity of active methylene compounds in carbonyl condensation reactions and the versatility of aldol products in forming new carbon-carbon bonds and functional groups. Explore the transformation possibilities and applications in organic synthesis.
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Presentation Transcript
Carbonyl Condensation Reactions Crossed Aldol Reactions -Dicarbonyl compounds are sometimes called active methylene compounds because they are more reactive towards base than other carbonyl compounds. 1,3- Dinitriles and -cyano carbonyl compounds are also active methylene compounds. 3
Carbonyl Condensation Reactions Useful Transformations of Aldol Products The aldol reaction is synthetically useful because it forms new carbon-carbon bonds, generating products with two functional groups. -Hydroxy carbonyl compounds formed in aldol reactions are readily transformed into a variety of other compounds. Figure 24.3 Conversion of a -hydroxy carbonyl compound into other compounds 4
