Classification of Drugs Acting on Central Nervous System - Overview by Dr. Kumari Anjana

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Explore the classification of drugs affecting the central nervous system as presented by Dr. Kumari Anjana, an Assistant Professor in Veterinary Pharmacology & Toxicology at Bihar Veterinary College. The central nervous system plays a vital role in coordinating various body activities and responses to the environment. The classification includes CNS stimulants and depressant drugs, each with their subcategories based on their actions and clinical uses. Gain insights into the intricate world of pharmacology impacting the CNS.

  • Drugs
  • Central Nervous System
  • Classification
  • Veterinary Pharmacology
  • CNS

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  1. Classification of drugs acting on Central Nervous System Dr. Kumari Anjana Assistant Professor Deptt. of Veterinary Pharmacology & Toxicology Bihar Veterinary College, Bihar Animal Sciences University, Patna

  2. Classification of drugs acting on Central Nervous System The CNS is an extremely Complex and heterogeneous system. It is the major coordinating system of the body & source of adjustment of an organism to its environment. Function-rapid communication system and is responsible for moment to moment control of various body activities. It regulates-rapidly changing visceral events, muscle contractions, secretions of some endocrine glands and functioning of the body system.

  3. Classification of drugs acting contd on CNS The CNS is more sensitive to effects of drugs than any other system of the body. A large number of drugs influence the CNS as a major part of their therapeutic effect (e. g,. anaesthesia), side effect & toxic effect, divided into two major groups: CNS stimulants drugs CNS depressant drugs

  4. CNS stimulants drugs Classification 1. On the basis of part of CNS where drug act: Spinal Stimulants or convulsants: Strychnine, picrotoxin Medullary Stimulants: Doxapram, Bemegride, Picrotoxin, Nikethamide, Leptazol Cortical Stimulants: Cocaine, amphetamine, methylxanthines.

  5. CNS stimulants drugs contd Classification 2. On the basis of action (Direct or Indirect): Direct acting stimulants : Strychnine, picrotoxin and xanthenes derivatives. Indirect (Reflexly) acting stimulants: lobeline, ammonia, Veratrum, nicotine.

  6. CNS stimulants drugs contd Classification 3. On the basis of clinical uses: Analeptics: Nikethamide, bemegride, doxapram. Psychostimulents: Amphetamines, methylphenidate, cocaine, methylxanthines, caffeine, theophylline. Cerebroactive drugs: Piracetam, dihydroergotoxine, Pyritinol.

  7. CNS depressant drugs Classification Tranquillizer sedatives : Chlorpromazine, Azaperone, Droperidol, Haloperidol. (Neuroleptics, Ataractics, Tranquillizers) Hypnotic sedatives : Chloralhydrate, Xylazine, Detomidine, Medetomidine, Phenobarbitone, Diazepam, Zolazepam.

  8. CNS depressant drugs contd Classification General Anaesthetics: Ether, Halothane, Enflurane, Isoflurane, Chloroform, Methoxyflurane Analgesics : Acetylsalicylate, Salicylate, Phenylbutazone, Isopyrin, Ibuprofen

  9. CNS depressant drugs contd Classification Central muscle relaxants: Guaiphenesin, Mephenesin. Anticonvulsants : Phenobarbitone, Phenytoin, Diazepam, Carbamazepine, (Antiepileptics) Ethosuximide Neuroleptanalgesics: Fentanyl + Droperidol

  10. Thank You

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