Clinical Lab Testing Services and CPIC Guidelines Overview
Discover a comprehensive list of clinical lab testing services and accrediting bodies utilizing CPIC guidelines. Explore resources, publications, and relevant information for implementing CPIC recommendations in personalized medicine and pharmacogenomics.
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Updated gantt on CPIC website https://cpicpgx.org/member-resources/
Clinical lab testing services and laboratory-related accrediting bodies that use CPIC guidelines in their reports and information. Institution Company Aegis Relevant Pubmed IDs or URLs (if applicable) http://www.ncbi.nlm.nih.gov/gtr/labs/505511/ http://amp.org/publications_resources/position_statements_letters/documents/AMPendorsementoftheCPICinitiativ e2015-10-26.pdf http://www.aruplab.com/pain-management/pharmacogenetics http://www.cap.org/ShowProperty?nodePath=/UCMCon/Contribution%20Folders/WebContent/pdf/pharmacogeno mics-gene-drug-pairs.pdf http://www.gbcbiotech.com/farmacogenomica/ http://genelex.com/physicians/pgx-risk-charts/ Association for Molecular Pathology ARUP Laboratories College of American Pathologist GBC biotech Genelex GenesFX DNAdose News http://www.genesfx.com.au/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=45&cntnt01returnid=27 Goutpal.com http://www.goutpal.com/5465/asian-allopurinol-dosing-dont-bear-the-scars/ GSK http://viapath.maze-staging.com/sites/default/files/upload/InnovationAcademy/DrColinSpraggs.pdf Idgenetix Illumina http://www.idgenetix.com/our-tests/idgenetix-tests https://www.illumina.com/content/dam/illumina-marketing/documents/clinical/ https://www.inova.org/medimap/resources/publications-references Inova Millennium Health Molec Diag Lab MD labs My Genes Rx Nerio Medical OneOme, LCC https://www.ncbi.nlm.nih.gov/gtr/labs/506028/ http://www.mdl-labs.com/providers/tests/CYP2C19 https://cpicpgx.org/implementation/ http://mygenesrx.com/us/resources/ http://www.neriomedical.com/#!recent-news/ch2w https://oneome.com/gene-detailshttps://oneome.com/guidelines http://www.personalis.com/cpic-clinical-pharmacogenetics-implementation-consortium-of-the-pharmacogenomics- research-network/ http://education.questdiagnostics.com/insights/36 https://rxight.com/resources/ http://summitmolecular.com/index.php/articles http://translationalsoftware.com/background.html http://vapainsolutions.com/index.php/products/genetic-testing http://youscript.com/blog/category/personalized-medicine/cytochrome-p450/ Personalis Quest Diagnostics RxIGHT Summit Molecular Translation.Software Virginia Pain soln You Script
Page views of CPIC guidelines as posted on Guidelines.gov Views (7/17/2015- 7/16/2016) Views (7/1/2016- 4/30/2017) Guideline Posted 1838 2606 2960 2087 2286 2277 2231 1793 2059 2052 2005 2490 1766 2412 3014 2256 HLA-B genotype and abacavir HLA-B genotype and allopurinol CYP2D6 and CYP2C19 and TCAs TPMT genotype and thiopurine CYP2C19 genotype and clopidogrel therapy: 2013 update HLA-B genotype and carbamazepine CYP2D6 genotype and codeine therapy: 2014 update DPYD genotype and fluoropyrimidine IFNL3 (IL28B) genotype and PEG interferon- based regimens Ivacaftor therapy in the context of CFTR genotype. SLCO1B1 and simvastatin-induced myopathy: 2014 update Rasburicase therapy in the context of G6PD deficiency genotype CYP2C9 and HLA-B genotypes and phenytoin dosing. CYP3A5 genotype and tacrolimus dosing. CYP2D6 and CYP2C19 and SSRIs UGT1A1 and atazanivir 7/26/2013 7/26/2013 7/26/2013 7/26/2013 2/14/2014 2/14/2014 8/29/2014 8/29/2014 8/29/2014 12/5/2014 3/13/2015 3/13/2015 9/11/2015 1/8/2016 7/15/2016 12/08/2016 1806 3036 4432 2236 2475 3592 2799 2467 2125 1928 2155 2348 3102 1819 n/a n/a
Number of attendees at monthly CPIC teleconferences continues to trend upwards. CPIC Attendance 80 70 60 50 40 30 20 10 0 Feb., 2015 Jan., 2016 Feb., 2016 Jun., 2016 Jan., 2017 Feb., 2017 Jun., 2017 Oct., 2014 Oct., 2015 Oct., 2016 Jul., 2014 Nov., 2014 Dec., 2014 Apr., 2015 Jul., 2015 Nov., 2015 Dec., 2015 Apr., 2016 Nov., 2016 Dec., 2016 Apr., 2017 Jul., 2017 Sept., 2014 Sept., 2015 Sept., 2016 Mar., 2015 Mar., 2016 Mar., 2017 May., 2017 May, 2015 Aug., 2015 May. 2016 Aug., 2016
CPIC guideline (and guideline update) accesses via multiple methods: on www.cpicpgx.org, on www.pharmgkb.org, from PubMed Central, and from CPT s website. CPT downloads (1/1/2015 to 7/31/ 2017)b 553c 3161 797c not available 460c 2799c not available not available 1181c 1315c not available Page Views on CPIC 8/1/16-8/1/17 Page Views on PharmGKB 8/1/16-8/1/17 PubMed Central downloads (7/1/2014 - 3/31/2017)a Guideline Tricyclic antidepressants and CYP2D6 and CYP2C19 SSRIs and CYP2D6 and CYP2C19 Warfarin and CYP2C9 and VKORC1 Clopidogrel and CYP2C19 Abacavir and HLA-B Codeine and CYP2D6 Thiopurines and TPMT Fluoropyrimidines and DPYD Simvastatin and SLCO1B1 Allopurinol and HLA-B Carbamazepine and HLA-B 2678 2600 2412 2061 1898 1602 1489 1092 970 859 783 13713 8170 10329 9429 4473 11815 7045 4822 4034 2557 2783 9914 2960 (5/2016 to 3/2017) 9205 10661 3616 13857 7506 5644 9416 2634 3777 Voriconazole and CYP2C19 Phenytoin and CYP2C9 and HLA-B Tacrolimus and CYP3A5 Ivacaftor and CFTR 762 741 694 635 1996 2902 2825 1188 not available 931 (9/2016 to 8/2017) 1272 2341 428 (published 12/2016) 1241 1725 133 Ondansetron and Tropisetron and CYP2D6 Atazanavir and UGT1A1 Rasburicase and G6PD Peg-interferon alpha and IFNL3 575 564 427 318 1561 2187 1660 1040 not available 544 (6/2016 to 2/2014) 1184 (9/2016 to 8/2017) 2954 309 (published 4/2017) 1336 770 385
Academic and health center users of CPIC guidelines (as of Sept 2017) Boston Children's Hospital Brigham and Women s Hospital/Harvard Children s Minnesota Cincinnati Children's Hospital Medical Center Clearview Cancer Institute Cleveland Clinic Dr. Margarete Fischer-Bosch-Institute Duke Center for Personalized & Precision Medicine El Camino Hospital Personalized Medicine Portal (powered by DNAdirect) Erasmus MC Fullerton Genetics Center Geisinger Health System I.M.P. Institute of Predictive Medicine Indiana Univ Levine Cancer Institute Mayo Clinic, Rochester, MN Medical College of Wisconsin Mission Health Moffit Cancer Center Mt. Sinai Health System https://cpicpgx.org/implementation/ https://cpicpgx.org/implementation/ http://www.cincinnatichildrens.org/service/g/genetic-pharmacology/default/ https://cpicpgx.org/implementation/ http://my.clevelandclinic.org/cph/education/newsletter/cph-year-end-2013.aspx https://cpicpgx.org/implementation/ https://precisionmedicine.duke.edu/ethical-social-legal-issues/guidelines https://elcaminogmi.dnadirect.com/grc/patient-site/warfarin-response/references.html https://cpicpgx.org/implementation/ PMID: 24316779 https://cpicpgx.org/implementation/ I.M.P. Institute of Predictive Medicine, PMID: 24807457 https://cpicpgx.org/implementation/ http://www.mayomedicallaboratories.com/interpretive-guide/?alpha=T&unit_code=62751 https://cpicpgx.org/implementation/ https://cpicpgx.org/implementation/ http://moffitt.org/research--clinical-trials/individual-researchers/howard-l-mcleod-pharmd http://icahn.mssm.edu/research/institutes/institute-for-personalized-medicine/for-researchers- and-innovators/clipmerge-pharmacogenomics-project http://www.northshore.org/individualized-medicine/clinical-capabilities/pharmacogenomics/ https://www.northshore.org/pharmacogenomics/pharmacogenomics-clinic/ PMID: 22594506 https://cpicpgx.org/implementation/ http://www.stjude.org/pg4kds/implement https://cpicpgx.org/implementation/ https://cpicpgx.org/implementation/ North Shore Univ HealthSystem Northwestern Medicine Ohio State Univ Peking Univ First Hospital St. Jude Children s Research Hospital Univ Hospital Schleswig-Holstein Univ of Adelaide
