Comprehensive Data Management and Sharing Process for SASCO Research Programs

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Explore the detailed steps involved in managing and sharing data for SASCO research initiatives, from identification to validation and finalization. Learn about the overarching goal of data sharing and the role of partners in the ecosystem.

  • Data Management
  • Research Programs
  • Data Sharing
  • SASCO
  • Data Services

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  1. SASCO Data Management Update Andrea Denton, MILS (she/her) Research & Data Services Manager Claude Moore Health Sciences Library November 2023

  2. For Today Data management and sharing ecosystem for SASCO The path to sharing data My role and our partners

  3. Overarching goal: data (and resource) sharing

  4. NCI Division of Cancer Biology support of multiple research programs Six consortia including Cancer Systems Biology Consortium (CSBC) Portal aims to synthesize and expose the activities and outputs of the consortia

  5. CCKP Facets/Filters

  6. Our records

  7. Our records

  8. So how do records get there?

  9. Step 1: Identification What studies are eligible for inclusion in the CCKP? Current workflow: Published as article Cite SASCO award Indexed by PubMed

  10. Step 2: Initial Annotation (description) Publication Journal, Year, etc. Tumor type, Assay, etc. What datasets are associated

  11. Step 3: Additional Annotation (description) Describe any deposited datasets Species Tissue Tumor Type Assay

  12. Annotations through a manifest (spreadsheet)

  13. Step 4: Annotation Validation & Finalization Annotations are checked Record is released in the CCKP

  14. Other scenarios: deposit No mandated or logical repository Where do we put data so it can be accessed by other researchers? If not already deposited, consider Synapse

  15. Synapse Data storage platform maintained by Sage Bionetworks NIH-designated generalist repository Set up Synapse Projects Contact MC2 Get certified (I am) Can be used for storage (no size limits?) With the goal of collaboration and/or sharing When ready, sync with CCKP

  16. Resources, too

  17. Going forward As papers are published or resources shared (e.g. Github) I ll watch, but MC2 does as well We (Andrea) complete the annotation (description) in the MC2 Data Curator App I ll reach out for input

  18. Going forward Continue to attend CSBC monthly events and training, including the CSBC / PS-ON Resource & Data Sharing Working Group Respond to MC2 requests for participation, e.g. piloting some of their processes/apps Communicate with MC2 and others about our needs Representing ancestry, e.g. add to annotation fields? Watch for future developments (e.g. can AI help with annotation) Can reach out to MC2 about use of Synapse

  19. Here to help! Andrea Denton andrea@virginia.edu (also assistance with data management and sharing issues beyond SASCO, e.g. writing DMSPs)

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