Cutting-Edge Medical Biochemistry Research at Dokuz Eylul University
The Department of Medical Biochemistry at Dokuz Eylul University is a hub of advanced research and education in biochemistry and related fields. Established in 1982, the department offers Master's and Doctorate programs, focusing on theoretical knowledge, laboratory skills, research capabilities, and scientific communication. The department has a track record of successful graduates and pioneering research projects funded by prestigious organizations. Ongoing and completed projects cover a wide range of topics, from cancer treatments to neuroinflammation studies. The department is dedicated to pushing boundaries and making significant contributions to the field of medical biochemistry.
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Dokuz Eylul University Institute of Health Sciences Department of Medical Biochemistry
The Department of (Medical) Biochemistry was founded in 1982 with the approval of High Council of Education (YOK) under the umbrella of the Medical School. The academic faculty of the department is composed of faculty members competent in different areas of biochemistry/medical biochemistry. The Master s and Doctorate degree programmes of Medical Biochemistry has been started in the 1985-1986 academic year. To date, 39 Master's and 37 PhD students have graduated.
The objectives of this programme are to educate individuals having an advanced level of basic and up-dated theoretical and laboratory information in basic biochemistry, medical biochemistry and closely related fields, to train students in basic laboratory skills as well as those skills necessary for performing independent research: to train them in advanced data searching, project writing, project management, international scientific communication, and writing of scientific articles.
Completed Current Tbitak Projects T bitak-1003 2019-2022 Development of a New Topical Treatment Method for Macular Corneal Dystrophy T bitak-1001 2018-2021 Evaluation of Synergistic Effect of the Metformin and Dichloroacetate on Mitochondrial Energy Metabolism and Cetuximab Chemosensitivity in Oral Cavity Cancer: Drug Repositioning T bitak-1001 2015-2018 Examination of the Functional Effects of Matrix Metalloproteinase-9 on Voltage-Gated Sodium Channel Nav1.5 and 1 Regulation in Metastatic MDA-MB-231 Human Breast Cancer Cells T bitak-2015-2017 Investigation of the Apoptotic Effects and Their Relationship with Signal Transduction Pathways of Curcumin Quercetin and Curcumin Quercetin Combination on Chronic Myeloid Leukemia Cells and Normal Mononuclear Cell Lines
Yrmekte olan Projeler TUSEB- 2023-2025 Investigation of the Potential Anti-tumoral Effect of the Circadian Rhythm-Related CRY1-Specific M47 Molecule in Prostate Cancer under Normal and Extended Lighting Conditions TUSEB- 2023-2025 Evaluation of the Relationship of Serum Albumin, Creatinine, Uric Acid, Magnesium and CRP Values with the Development of Type 2 DM, Cardiovascular Disease, Dementia and Alzheimer's: Bal ova's Heart (BAK) Prosthetic Cohort Study T B TAK- 2022-2025 Development of New Bioactive Peptide Hydrogels for 3D Cancer Modeling Applications DE -BAP 2023-2024 Neuroinflammation of Curcumin and Quercetin Polyphenol Combination in Sepsis Modeled Rats and Examination of its Preventive Effect on the Blood-Brain Barrier
Completed Current Master's Thesis Projects DE -BAP 2022-2023 Synthesis of Metformin-loaded PLGA-PEG (Poly-D,L-lactic-Co-Glycolic Acid-Poly Ethylene Glycolic Acid) Nanoparticles and In vitro Examination of their Anticancer Effects on Follicular Thyroid Cancer (FTC-133) Cell Line DE -BAP 2021-2022 Development of an in situ collagen zymography method to determine the localization and activity of collagenases in thyroid cancer cell lines DE -BAP 2017 2019 Examination of the molecular and behaviorally effects of high polyphenol olive oil on neurogenesis in brain tissue in old rats. DE BAP 2013-2015 Examining the effects of Resveratrol and Sirtuin1 on p53(+/+) and p53(-/-) colon cancer cells
Completed Current PhD Thesis Projects DE -BAP 2018-2021 Effect of N-MYC Downstream Regulated Gene-2 Expression on Epithelial Mesenchymal Transformation in Thyroid Cancer DE -BAP 2017-2019 Examining the Role of HIF-1alpha-Related Mitochondrial Glucose Metabolism in the Hypoxic Microenvironment of Head and Neck Cancer Cells DE -BAP 2012-2015 Determination of the possible relationship between RhoC-GTPase and extracellular proteolysis in colon cancer cells DE -BAP 2016-2019 Investigation of the amyloid beta plaque dissolution activities of polyphenolic compounds in differentiated-SH-SY5Y cells and examination of the in vitro effects of differentiated cells on blood-brain barrier integrity DE BAP and T B TAK 2017-2019 Investigation of the Effects of Casticin on Survival and Death Pathways of Stem Cell-Like and Mature Acute Myeloid Leukemia Cell Lines.
