Disease Burden Trends in the U.S.

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The burden of disease in the U.S. has seen reductions in premature death rates, but remains higher compared to similar countries. Leading causes of death include cancer and circulatory diseases. Despite decreasing trends, the gap in disease burden between the U.S. and other nations has slightly widened.

  • Disease burden
  • U.S. healthcare
  • Global health
  • Mortality rates

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  1. What do we know about the burden of disease in the U.S.? Peterson-Kaiser Health System Tracker

  2. Lower rates of premature death have driven reduction in disease burden in the U.S., after adjusting for age Age standardized disability adjusted life year (DALY) rate per 100,000 population, 1990 - 2010 1990 2010 30000 25,633 25000 21,956 20000 15,130 15000 11,447 10,509 10,503 10000 5000 0 DALYs Years of Life Lost Years Lived with Disability Source: Institute for Health Metrics and Evaluation. Global Burden of Disease Study 2010 (GBD 2010) Data Downloads, available here: http://ghdx.healthdata.org/global-burden-disease-study-2010-gbd-2010-data-downloads Peterson-Kaiser Health System Tracker

  3. Disease burden is higher in the U.S. than in comparable countries Age standardized disability adjusted life year (DALY) rate per 100,000 population, 2010 United States 21,956 United Kingdom 20,384 Belgium 20,314 France 19,860 Austria 19,782 Germany 19,527 Netherlands 19,480 Canada 19,392 Comparable Country Average 19,071 Australia 18,701 Sweden 18,546 Switzerland 17,877 Japan 15,922 - 5,000 10,000 15,000 20,000 25,000 Source: Institute for Health Metrics and Evaluation. Global Burden of Disease Study 2010 (GBD 2010) Data Downloads, available here: http://ghdx.healthdata.org/global-burden-disease-study-2010-gbd-2010-data-downloads Peterson-Kaiser Health System Tracker

  4. Though disease burden is decreasing in the U.S. and other countries, the gap has widened slightly Age standardized disability adjusted life year (DALY) rate per 100,000 population, 1990 - 2010 United States Comparable Country Average 30000 25,633 24,753 25000 23,390 23,276 22,695 22,120 21,956 20,936 19,687 19,071 20000 15000 10000 5000 0 1990 1995 2000 2005 2010 Source: Institute for Health Metrics and Evaluation. Global Burden of Disease Study 2010 (GBD 2010) Data Downloads, available here: http://ghdx.healthdata.org/global-burden-disease-study-2010-gbd-2010-data-downloads Peterson-Kaiser Health System Tracker

  5. Cancer and circulatory diseases are the leading causes of death in the U.S. Age standardized death rate per 100,000 population, both sexes, 2013 Circulatory 183 Cancer and Tumors 144 Nervous System 64 Injuries 48 Endocrine (diabetes) 42 Chronic respiratory 39 Common infectious diseases 21 Cirrhosis of the liver 12 Mental health and substance use disorders 10 Neonatal 5 - 20 40 60 80 100 120 140 160 180 200 Source: Institute for Health Metrics and Evaluation. Global Burden of Disease Study 2013 (GBD 2013) Data Downloads, available here: http://ghdx.healthdata.org/global-burden-disease-study-2013-gbd-2013-data-downloads Peterson-Kaiser Health System Tracker

  6. Mental health and circulatory disorders are the leading causes of disease burden in the U.S. Age standardized disability adjusted life years (DALYs) rate per 100,000 population, both sexes, 2013 Mental health and substance use disorders 3,266 Circulatory 3,261 Cancer and Tumors 3,133 Musculoskeletal disorders 2,804 Injuries 2,519 Endocrine (diabetes) 1,773 Nervous System 1,487 Chronic respiratory 1,424 Neonatal 672 Skin diseases 629 - 500 1,000 1,500 2,000 2,500 3,000 3,500 Source: Institute for Health Metrics and Evaluation. Global Burden of Disease Study 2013 (GBD 2013) Data Downloads, available here: http://ghdx.healthdata.org/global-burden-disease-study-2013-gbd-2013-data-downloads Peterson-Kaiser Health System Tracker

  7. Mental health and musculoskeletal disorders are the leading causes of years lost to disability in the U.S. Age standardized years lived with disability (YLD) rate per 100,000 population, both sexes, 2013 Mental health and substance use disorders 2,825 Musculoskeletal disorders 2,751 Endocrine (diabetes) 1,010 Nervous System 861 Chronic respiratory 830 Injuries 636 Skin and subcutaneous diseases 612 Circulatory 510 Cancer and Tumors 220 Common infectious diseases 77 - 500 1,000 1,500 2,000 2,500 3,000 Source: Institute for Health Metrics and Evaluation. Global Burden of Disease Study 2013 (GBD 2013) Data Downloads, available here: http://ghdx.healthdata.org/global-burden-disease-study-2013-gbd-2013-data-downloads Peterson-Kaiser Health System Tracker

  8. Cancer and circulatory diseases are the leading causes of years of life lost in the U.S. Age standardized years of life lost (YLL) rate per 100,000 population, both sexes, 2013 Cancer and Tumors 2,913 Circulatory 2,751 Injuries 1,882 Endocrine (diabetes) 763 Nervous System 627 Chronic Respiratory 594 Neonatal 445 Mental health and substance use disorders 441 Cirrhosis of the liver 342 Common infectious diseases 335 - 500 1,000 1,500 2,000 2,500 3,000 3,500 Source: Institute for Health Metrics and Evaluation. Global Burden of Disease Study 2013 (GBD 2013) Data Downloads, available here: http://ghdx.healthdata.org/global-burden-disease-study-2013-gbd-2013-data-downloads Peterson-Kaiser Health System Tracker

  9. U.S. disease burden has decreased in past two decades for circulatory, cancer, injuries, and neonatal disorders Age standardized disability adjusted life years (DALYs) rate per 100,000 population, both sexes, 1990 and 2013 1990 2013 2948 Mental and behavioral disorders 3266 5134 Circulatory* 3261 3862 Cancer and Tumors* 3133 2657 Musculoskeletal disorders 2804 3519 Injuries* 2519 1542 Endocrine (diabetes) 1773 1426 Nervous System 1487 1460 Chronic respiratory 1424 922 Neonatal* 672 634 Skin diseases 629 0 1000 2000 3000 4000 5000 6000 * Indicates statistically significant change from 1990 to 2013 Source: Institute for Health Metrics and Evaluation. Global Burden of Disease Study 2013 (GBD 2013) Data Downloads, available here: http://ghdx.healthdata.org/global-burden-disease-study-2013-gbd-2013-data-downloads Peterson-Kaiser Health System Tracker

  10. Other countries have seen improvement in similar areas as U.S., but some at faster rates Percent change in age standardized disability adjusted life year (DALY) rate per 100,000 population, 1990 - 2013 United States Comparable Country Average Circulatory Cancers Injuries Neonatal 0% -5% -10% -15% -20% -19% -22% -25% -27% -30% -28% -35% -35% -36% -40% -39% -45% -47% -50% Source: Institute for Health Metrics and Evaluation. Global Burden of Disease Study 2013 (GBD 2013) Data Downloads, available here: http://ghdx.healthdata.org/global-burden-disease-study-2013-gbd-2013-data-downloads Peterson-Kaiser Health System Tracker

  11. For males, disease burden most caused by circulatory diseases; for females, mental health is leading cause MALES FEMALES Age standardized disability adjusted life years (DALYs) rate per 100,000 population, males in the U.S., 2013 Age standardized disability adjusted life years (DALYs) rate per 100,000 population, females in the U.S., 2013 Circulatory Mental health/substance use 4,114 3,346 Cancer and Tumors Musculoskeletal 3,615 3,203 Injuries Cancer and Tumors 3,518 2,741 Mental health/substance use Circulatory 3,181 2,494 Musculoskeletal Endocrine (diabetes) 2,375 1,667 Endocrine (diabetes) Nervous System 1,918 1,614 Chronic respiratory Injuries 1,508 1,527 Nervous System Chronic respiratory 1,371 1,365 Neonatal Skin diseases 720 624 Skin diseases Neonatal 636 620 - 1,000 2,000 3,000 4,000 5,000 - 1,000 2,000 3,000 4,000 Source: Institute for Health Metrics and Evaluation. Global Burden of Disease Study 2013 (GBD 2013) Data Downloads, available here: http://ghdx.healthdata.org/global-burden-disease-study-2013-gbd-2013-data-downloads Peterson-Kaiser Health System Tracker

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