
Efficient Algorithms for Frequent Pattern Mining with Non-Overlapping Inversions
Explore efficient algorithms for identifying frequent patterns in biological sequences with non-overlapping inversions, a crucial method in bioinformatics for studying sequence conservation and evolution.
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Frequent Pattern Mining with Non-overlapping Inversions Da-Jung Cho, Yo-Sub Han, and Hwee Kim Proceedings of International Conference on Language and Automata Theory and Applications (LATA), Nice, France, March 2-6, 2015, pp. 121-132 Speaker: Kuan-Lin Lai Date: Oct. 29, 2019
Abstract Frequent pattern mining is widely used in bioinformatics since frequent patterns in bio sequences often correspond to residues conserved during evolution. In bio sequence analysis, non-overlapping inversions are well-studied because of their practical properties for local sequence comparisons. We consider the problem of finding frequent patterns in a bio sequence with respect to non-overlapping inversions, and design efficient algorithms.
Inversion v.s. Reversal ? = AGCTAGCTAG reversal(?): GATCGATCGA inversion(?): CTAGCTAGCT
Frequent Pattern Mining with Non-overlapping Reversal EX: ? = AGCTAGCTAG m = 4 r = 3 Find all pattern ? with length m s.t. ???(?,?) ? TCGA: 7 A G C T A G C T A G T C G A T C G A T C G A T C G A
Construct Reversal Graph ? = AGCTAGCTAG m = 4