Evaluation of Pathologies Presenting as Suspicious for Follicular Neoplasia and Follicular Neoplasia in Thyroid Fine Needle Aspiration Biopsies
Thyroid fine-needle aspiration biopsy is crucial for distinguishing between benign and malignant nodules, aiding in appropriate treatment decisions. This study analyzed 120 patients with Suspicious for Follicular Neoplasia and Follicular Neoplasia using the Bethesda system, assessing demographics, final pathologies, and treatments outcomes.
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Evaluation of Pathologies Presenting as Suspicious For Follicular Neoplasia And Follicular Neoplasia (FNS/FN) in Thyroid Fine Needle Aspiration Biopsies Student: Esra Nur G l Mentor: Prof.Dr. Yeliz Emine Ersoy
Thyroid fine-needle aspiration biopsy is the procedure of taking sample from thyroid lesions under ultrasound guidance. The prevalence of thyroid nodules is high but most of these nodules are benign. Therefore, it is important to differentiate benign/malign in terms of the course of treartment to save the patient from unnecessary surgery.
The Bethesda system is used to standardize thyroid fine-needle aspiration biopsy results between pathologists and surgeons.
METHOD Between October 2010 and October 2020, a total of 120 patients with Suspicious for Follicular Neoplasia and Follicular Neoplasia (FNS/FN) (Bethesda category 4) were detected in the thyroid fine needle aspiration biopsy results, who applied to the Bezmialem Vak f University Medical Faculty Hospital General Surgery Department, patients were included in the study. Demographic characteristics, medical history and clinical characteristics of the patients who were followed up with this pathology result or for whom a surgical decision was made, additional final pathologies and additional treatments of those who underwent surgery, and the final status of those who underwent follow-up will be evaluated.
RESULTS Among the120 patients, 98 were women(81.66%) and 22 were men(18.33%) with the mean ages of 48.18 and 51.32, respectively. In 25(20.83%) patients whose final pathology results were malignant, the mean age was 47 and the mean nodule size was 2.5 cm. In 95 patients (79.16%) whose final pathology results were benign, the mean age was 49.2 and the mean nodule size was 2 cm.
There is no significant difference between size, age, hormonal status, nodule borders, thyroiditis, and the biopsy method used in patients whose final pathology results were benign or malignant.
CONCLUSION As a result of the study, no distinctive correlation was found that could be helpful in concretization of the treatment approach in this category of patients. Bethesda IV is a heterogeneous category and we believe that further larger studies are needed to determine a clear treatment approach.
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