
Ferrous Gluconate: Properties, Uses, and Antidotes
Discover the formula, preparation, properties, and uses of ferrous gluconate, a vital haematinic with minimal side effects compared to other iron salts. Explore how antidotes interact with poisons, neutralizing and eliminating toxins effectively.
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Presentation Transcript
Ferrous gluconate Formula- C12H22O14Fe.2H2 Preparation Gluconic acid is first prepared by oxidation of glucose by dilute nitric acid. Then barium carbonate is added to get the barium salt.This is treated with ferrous sulphate and the precipitated barium sulphate is removed and the filtrate is concentrated and cooled to get crystals. It can also be prepared by double decomposition reaction between calcium gluconate and ferrous sulphate .The calcium sulphate is insoluble and filtered off.The solution of ferrous gluconate is concentrated to yield the grey powder [-OOC-(CHOH)4-CH2OH]Ca2++ FeSO4 CaSO4 [-OOC-(CHOH)4-CH2OH]Fe2++
Properties: It is yellowish grey or pale greenish yellow fine powder with slight odour resembling burnt sugar. It is soluble in water and almost insoluble in alcohol. its aqueous solutions are acidic. Uses It is used as haematinic. It causes less side effects than other ferrous salts including ferrous sulphate. it is also used for the preparation of ferrous gluconate tablets
Poisons and antidotes POISON: Poison is any substance that when introduced into or absorbed by the body causes illness and death Antidotes Antidotes are the substances which interact with an indigested toxic substance(counter acts). These substances perform following functions
They neutralize the poison They convert the toxic substances to non toxic or less toxic substance by forming complex ,more polar or insoluble derivatives They adsorb or absorb and facilitate the elimination of toxic substances from the site of action. The complexes formed between the toxic substances and the antidote should be easily and quickly removed from the site and should reach eliminating system