Fluid Compartments and Renal Sodium Handling in the Urinary System
Explore the essential concepts of fluid compartments, sodium control in the extracellular fluid, and renal responses to volume changes in the urinary system module. Learn about the composition of intracellular and extracellular fluids, renal sodium handling, and more. Get insights from educators at the University of Basrah Al-Zahraa Medical College.
Download Presentation
Please find below an Image/Link to download the presentation.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author. If you encounter any issues during the download, it is possible that the publisher has removed the file from their server.
You are allowed to download the files provided on this website for personal or commercial use, subject to the condition that they are used lawfully. All files are the property of their respective owners.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author.
E N D
Presentation Transcript
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE The module: URINARY SYSTEM MODULE Session 4 Lecture 1 MODULE STAFF: Prof.Mahmood Shakir Dr.Khaldoon Sadek Dr.Adnan Othafa Ass.Prof.Firas Shakir Dr. Safaa Almatook Clinically Orientated Anatomy Publisher:Lippincott Williams and Wilkins:Seventh Edition: ISBN:9781451184471 Moore KL ,DalleyAF&Agur AMR For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE Learning out come 1-Fluid compartments 2-contrle sodium ion in ECF 3-renal response to ECF volume change For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO1 The body fluid is divided in to main compartments intracellular ICF and extracellular compartment ECF ,which in turn divide into interstitial and blood plasma.ECF is about 20% of 70 kg body weight i.e 14 L,11 L in the interstitial comp. and 3 L as plasma For more detailed instruction, any question, cases need help please post to the group of session.
UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 Composition ECF both plasma and interstitial fluid have the same ionic components since the separation is by highly permeable membrane the difference is in the presence of proteins in plasma main ionic electrolyte include sodium and chloride ICF in contrast to ECF has small amount of NaCl but contain potasium and phosphate almost no calcium ,magnisium ,sulfates and proteins For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 Renal Sodium handling Renal Sodium handling Na is the main ion of ECF ,main osmotic load, so it is the main determinant of volume Na is the main ion of ECF ,main osmotic load, so it is the main determinant of volume thus kidney control of Na can control plasma volume thus kidney control of Na can control plasma volume For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 Na ion balance Na ion balance if ingestion more than loss if ingestion more than loss ---- by by nephron nephron result in increase blood pressure result in increase blood pressure ----increase ECF because of increase ECF because of decreae decreae in fluid loss in fluid loss if increase in Na loss more than intake it will lead to more loss of fluid by if increase in Na loss more than intake it will lead to more loss of fluid by nephron nephron it will lead to reduction of ECF and decrease blood pressure due to it will lead to reduction of ECF and decrease blood pressure due to decrease plasma volume decrease plasma volume For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 How dose the body sense change in plasma volume? How dose the body sense change in plasma volume? Baroreceptors Baroreceptors: : 1 1- -low pressure receptors in the atria* low pressure receptors in the atria*bainbridge 2 2- -high pressure receptors in the aortic arch and carotid sinus high pressure receptors in the aortic arch and carotid sinus bainbridge reflex reflex Flow receptors Flow receptors at the macula at the macula densa densa Osmorecptors: Osmorecptors:with reabsorb water to regain osmotic balance reabsorb water to regain osmotic balance with increase osmosis due to high Na the body secrete ADH to increase osmosis due to high Na the body secrete ADH to For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 Summery renal response to plasma volume is by: if the ECF volume increase it excrete more NaCl if the ECF volume decrease it decrease the excretion of NaCl For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 Sodium handling by the Sodium handling by the nephron 67% reabsorbed in PCT 67% reabsorbed in PCT 25% in the loop of 25% in the loop of Henle Na Na- -K K- -ATP pump ATP pump pump pump Na from cell to exchange exchange fo fo K as a result Na pass from tubular lumen to the cell K as a result Na pass from tubular lumen to the cell passivly nephron Henle Na from cell to interstiatial interstiatial space by active space by active transpor transpor in passivly in For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 Renin system RAA decrease flow in the tubule stimulate macula densa to secrete renin with cosequence of angiotensin and sodium reabsorption Natriuretic peptides it is secreted in response to pressure change in the heart leading to increase sodium excretion and increse GFR For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE LO2 For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE For more detailed instruction, any question, cases need help please post to the group of session.
Ministry of higher Education and Scientific Researches UNIVERSITY OF BASRAH AL-ZAHRAA MEDICAL COLLEGE For more detailed instruction, any question, cases need help please post to the group of session.
