Frey’s Syndrome

Frey syndrome, described by Lucie Frey in 1923, manifests as sweating and flushing in the pre-auricular area post-salivary gland surgery. Common symptoms include flushing, sweating, burning, neuralgia, and itching. Diagnosis involves Minor Starch testing. Treatment options include intracranial division of the auriculotemporal nerve and botulinum toxin injections.

• Frey Syndrome
• Symptoms
• Diagnosis
• Treatment
• Salivary Gland Surgery

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Uploaded on Mar 14, 2025 | 0 Views

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Presentation Transcript

1. Frey s Syndrome

2. Frey syndrome was first described by Lucie Frey in 1923 and was termed Auriculotemporal syndrome. It described sweating and flushing in the pre auricular area in response to mastication or a salivary stimulus.

3. Introduction Commonly occur after salivary gland surgery, occurring in 62% of post parotidectomy patients 6 to 18 months after surgery . The previous sympathetic responses of sweating and flushing are now controlled by post ganglion parasympathetic fiber s.. Mastication, which releases acetylcholine from the parasympathetic nerve ndings , now induces sweating and flushing, which was a sympathetic cholinergic response before synkinesis of parasympathetic nerve fibers

4. Symptoms 1. The symptoms of Frey syndrome can include 2. flushing, 3. sweating, burning, 4. 5. neuralgia, and 6. itching. 7. Generally, the symptoms are mild but can result in discomfort as well as social anxiety and avoidance

5. Diagnosis Minor Starch testing Diagnosis of Frey syndrome is based on clinical history, but confirmatory testing can be done with a Minor starch-iodine test. The starch-iodine test consists of painting the patient s postsurgical affected region with iodine. Once dry, dry starch is then applied to the painted area, and a salivary stimulus is given. The starch turns blue/brown in the presence of iodine and sweat

6. Treatment Intracranial division of auriculotemporal nerve. Subcutaneous injection of botulinum toxin A into affected areas can be used to treat the postoperative symptoms of Frey syndrome.