Genetic Mutations and Rearrangements in Comparative Genomics

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Explore the differences between rearrangements and point mutations, analyze synteny blocks across species, and delve into the results and discussions on human vs. chimp genetic variations. Discover the impact on alignment coverage and potential next steps in genetic research.

  • Genetics
  • Mutations
  • Comparative Genomics
  • Alignment Coverage
  • Synteny Blocks

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Presentation Transcript


  1. Rearrangement vs. Point Mutations By Karl Menzel

  2. Is rearrangements or Point Mutations Faster

  3. Synteny Blocks and Chromosomes Mouse Human Chimp Human

  4. Data Reading and Sliding Window

  5. Results Human vs Chimp 1 67.5% Human vs Mouse 10 Rearrangements Alignment Coverage

  6. Discussion Need More Time and Data Next Steps: Affine Gap Penalty Maybe Look at specific Genes

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