Guidelines for Formulation Adjustments in Pharmacy Practice
Learn how pharmacists can reduce or enlarge formulas for pharmaceutical preparations, including calculations and handling formulas specified in proportional parts. Explore practical strategies for modifying formulations effectively in pharmacy practice.
Download Presentation
Please find below an Image/Link to download the presentation.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author. If you encounter any issues during the download, it is possible that the publisher has removed the file from their server.
You are allowed to download the files provided on this website for personal or commercial use, subject to the condition that they are used lawfully. All files are the property of their respective owners.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author.
E N D
Presentation Transcript
Principles of pharmacy practice Lec 1 Lecturer Dr Athmar Dhahir Habeeb Al-Shohani PhD in industrial pharmacy and pharmaceutical formulations athmar1978@uomustansiriyah.edu.iq athmar1978@yahoo.com athmar.habeeb.12@ucl.ac.uk
Reducing and enlarging formulas Pharmacists may have to reduce or enlarge formulas for pharmaceutical preparations in the course of their professional practice activities. Official (United States Formulary) formulas generally are based on the preparation of 1000 mL or 1000 g. Other formulas, as those found in the literature, may be based on the preparation of a dosage unit (e.g., 5 mL, 1 capsule) or another quantity (e.g., 100 mL). or manufacturing Pharmacopeia National
Calculations to reduce or enlarge formulas may be performed by a two-step process: Step 1. Using the following equation, determine the factor that defines the multiple or the decimal fraction of the amount of formula to be prepared: Quantity of formula desired Quantity of formula given =Factor (A factor greater than 1 represents the multiple of the formula, and a factor less than 1 indicates the fraction of the formula to be prepared). Step 2. Multiply the quantity of each ingredient in the formula by the factor to determine the amount of each ingredient required in the reduced or enlarged formula.
Formulas that specify proportional parts On occasion, a pharmacist may encounter an old formula that indicates the ingredients in parts rather than in measures of weight or volume. The parts indicate the relative proportion of each of the ingredients in the formula by either weight or volume, but not both. A formula for solid or therefore, may be considered in terms of grams, whereas a formula of liquids may be considered in terms of millilitres. semisolid ingredients,
