Herbal Remedy for Erectile Dysfunction in African Men
Herbal remedies have long been utilized in traditional African societies for various ailments. This study explores the potential of Morella serrata in rejuvenating sexual competence in male Wistar rats and addressing erectile dysfunction. The plant's historical uses in treating chest issues, enhancing male sexual performance, and managing other disorders are also highlighted. The research aims to provide valuable insights into the effects of M. serrata root extract on sexual enhancement, potentially offering new opportunities for managing erectile dysfunction in African men.
Uploaded on Feb 18, 2025 | 0 Views
Download Presentation
Please find below an Image/Link to download the presentation.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author.If you encounter any issues during the download, it is possible that the publisher has removed the file from their server.
You are allowed to download the files provided on this website for personal or commercial use, subject to the condition that they are used lawfully. All files are the property of their respective owners.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author.
E N D
Presentation Transcript
MORELLA SERRATA (LAM.) KILLICK STABILIZES BIOMEMBRANE AND REJUVENATES SEXUAL COMPETENCE IN MALE WISTAR RATS AOT Ashafa and S Sabiu
Introduction In traditional African societies, herbal remedies have been employed in the treatment of various diseases since time immemorial. However, general acceptability of herbal medicines has been limited by lack of defined chemical characterization, dose regimen and adequate toxicity data to evaluate their safety. The indiscriminate use of herbal remedies has often times led to major impairment or total damage of human functional organs.
Erectile dysfunction is the inability to develop and maintain an erection for satisfactory sexual intercourse or activity in the absence of an ejaculatory disorder such as premature ejaculation. Erectile dysfunction is the preferred term rather than impotence. There are no universally agreed criteria for how consistent the problem has to be and for what duration it needs to be present to fulfill the definition. At age 40, approximately 40% of men are affected. The rate increases to nearly 70% in men aged 70 years. The prevalence of complete ED increases from 5% to 15% as age increases from 40 to 70 years. Age was the variable most strongly associated with ED.
In the traditional medicine practice of the Xhosa, the plant is used to treat chest related problems such as asthma, coughing and shortness of breath. A decoction of the root tastes like ginger and causes irritation of the throat, therefore, the name umqhwetayo (the itchy one) (Schmidt et al., 2002). Among the Basotho of the eastern Free State Province, the decoction of the root is used for painful menstruation, cold, coughs and headaches (Moffet, 2010). and To enhance men sexual performance, hence the name Monna-motsho (black man). It is also used in the management of sugar related disorder and as laxative to treat constipation Morella seratta (Zukulu et al., 2012)
Before this study, there was dearth of information on the effect of M. seratta root extract on the sexual enhancement function of the plant yet it is used to enhance male sexual performance by the Basotho men. Preliminary investigation revealed that the plant is a potent remedy for bacterial and fungal infections. It was also discovered that it can be used in cancer management. Although this claim requires further analysis. Therefore, this study was aimed at providing information on the effect of the aqueous extract of this herb on sexual enhancement to determine whether it can give a lead to further management of erectile dysfunction in African men.
MATERIALS AND METHODS Plant collection, authentication and processing. Experimental animals Experimental protocol Sperm motility, viability and counts Testicular homogenate preparation Determination of biochemical parameters Membrane stabilizing activity Preparation of bovine red blood cell suspension Hypotonic solution induced hemolysis Heat-induced hemolysis Gas chromatography-mass spectrometric (GC-MS) analysis Data analysis
CONCLUSION: The results obtained from the various studies have shown that the root of M. serrata possessed aphrodisiac properties. The effect elicited by the extract at the tested doses could partly be attributed to its antioxidant and adaptogenic constituents. Overall, the data presented in this study have enriched biochemical information on the root extract of M. serrata as a viable source of phytonutrients that could be potentially useful for the development of aphrodisiac drugs. Thus lending scientific credence to its much touted sex enhancing attributes by the Basothos of the eastern Free State Province of South Africa.
ACKNOWLEDGEMENTS Institutional Research committee of the University of the Free State for financing the study (21142604). We also acknowledged the management of Lagos State University particularly Faculty of Science for the release of Dr Idowu Kazeem, Dr Teslim Ojuromi and Dr Tayo Ogundajo for Postdoctoral Fellowship at our institution UFS-Qwaqwa Campus. They made great impacts in their respective specialty and represented your University well.
Thank you Adupe eseun gaan
