Hypogonadism: Causes, Symptoms, and Treatment
Hypogonadism, including hypo-gonadotropic and secondary types, can result in decreased sperm and testosterone production. Learn about congenital abnormalities, eunuchoid proportions, and treatment options for restoring fertility and secondary sex characteristics.
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Presentation Transcript
Hypo gonadotropic Hypogonadism
Secondary hypogonadism is usually associated with similar decreases in sperm and testosterone production. Secondary hypogonadism is less likely to be associated with gynecomastia.
CONGENITAL ABNORMALITIES Sexual differentiation in all of these disorders is normal male . Phallic development during the third trimester is subnormal . Childhood growth is normal if gonadotropin deficiency is an isolated event . Pubertal development is incomplete or even absent, depending upon the degree of gonadotropin deficiency.
Eunuchoid proportions result when epiphyseal closure is delayed because of subnormal serum testosterone and its conversion to estradiol. An exception is if growth hormone is also subnormal . Midline defects (ie, cleft lip/palate) , unilateral renal agenesis ,uni or bilateral cryptorchidism , syndactyl or other skeletal abnormalities hyposmia or anosmia .
TREATMENT To develop secondary sex characteristics To build and sustain normal bone and muscle mass To restore fertility
