Immune Responses to Foot-and-Mouth Disease Virus in Guinea Pigs After Vaccination
This study investigates immune responses to foot-and-mouth disease virus in guinea pigs after vaccination with a canine adenovirus vector. Results show that the CAV2-based vector can express immunogenic FMDV antigens in rodents, providing protection against FMD in guinea pigs. The findings suggest that CAV-P1/3C could serve as a potential marker vaccine against FMD.
Download Presentation
Please find below an Image/Link to download the presentation.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author.If you encounter any issues during the download, it is possible that the publisher has removed the file from their server.
You are allowed to download the files provided on this website for personal or commercial use, subject to the condition that they are used lawfully. All files are the property of their respective owners.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author.
E N D
Presentation Transcript
immune responses to foot-and-mouth disease virus in guinea pigs after vaccination with canine adenovirus vector S.A. Lacour, A. De Vleeschauwer, L. Bakkali-Kassimi, S. Zientara, K. De Clercq, B. Klonjkowski ERA-NET ANIHWA Open Session of the EuFMD - Cascais Portugal 26-28 October 2016
CAV-P1-3C P1 Human adenovirus Canine adenovirus Transfection of DKE1 cells CAV-P1/3C
Assessment of protection Immune response Clinical symptoms viremia OS16
Conclusions CAV2-based vector can - express immunogenic FMDV antigens in rodents, - provide protection against FMD in guinea pigs - and suggest that CAV-P1/3C could be a potential marker vaccine against FMD OS16
