Influenza Disease Prevention and Transmission

Influenza disease prevention By Gehad Alzwai Roll no:2790 01

01 List Discuss 04 Symptoms of influenza disease Prevention of influenza disease 02 Discuss Different root of influenza virus transmission 03 Outline Treatment of influenza disease 02

Introduction Influenza disease commonly known flu is an infectious disease caused by (influenza virus). Influenza disease has many types A B and C. the most important one is type A which affect human pigs and birds and are the major cause of pandemic and epidemic influenza infection. 03

Concepts and Typology Type Features Manly affect human and animals and can be epidemic and pandimic influenza A Affect human only and can be epidemic and pandemic Influenza B Not either epidemic or pandemic Influenza C 04

01 List Symptoms of influenza disease 05

Symptoms of the Disease Nasopharynx :-sore throat Aches Systemic:Fever (usually high) Respiratory: -Coughing Gastric: -Vomiting Joints: -Aches 06

02 Outline Different root of influenza virus transmission 07

.There are two mechanisms for influenza virus transmission: First (main)mechanism -Exposure to large particile(above 5 um) respiratory droblet when someone sneezing or coughing. -These traveles only short distance (usually 1m or less)through the air 08

Second mechanism -Self contamination through hand to nose hand to eye hand to mouth transmission (toutching the T zone after touthhing a contaminated surface) -Small particile transmission at several meters 09

03 Outline Treatment of influenza disease 10

Treatment Anti-influenza agent A-neuroaminidase inhibitors(oral oseltemivir inhaled zanamivir IV peramivir) B- admantanine(amantadine rimantadine) Supportive care Include A-Hydration B-Rest 11

Anti-influenza agent A-neuroaminidase:(oseltamivir zanamivir peremivir) -They act against both type A and B and prevent the spread of infection within the respiratory tract. -These agents competitively and reversibly interacte with the active enzyme site to inhibit viral neuroaminidase activity B-admantanine:(amantadine rimantadine) -They act against type A only 12 -inhibit uncoating of viral RNA within the host cell

04 Discuss Prevention of influenza disease 13

Prevention How to Prevent influenza Disease Avoid close contact Stay at home 14

About prevention Clean your hands Clean distinfict surface Wear mask 15

Vaccination 16

Types of influenza vaccine: Types of influenza vaccine: 1-inactivated: -whole virus particle vaccine -subunit -split virus vaccine 2-live attenuated: -gives better effect for children (not recommend) 3 3- -Recombinant HA vaccine: Recombinant HA vaccine: -Trivalent -Quadrivalent -Supemtek 17

Conclusions -influenza is a highly contagious viral infection -Most of strains of H1N1 H3N2 are show resistance -Vaccine is the most effective way to prevent influenza disease 18

References Center of disease controlling (CDC) World health organization (WHO) Warren levinson review of medical microbiology and immunology (14thedition) Lippincotts pharmacology 5theddition (2012) Sekiya T, Ohno M, Nomura N, et al. Selecting and Using the Appropriate Influenza Vaccine for Each Individual. Viruses. 2021;13(6):971. Published 2021 May 24. doi:10.3390/v13060971 19

Thank you!! 20