Initial Physiological Response to Tissue Damage and Inflammation

The initial response to tissue damage includes acute or chronic inflammation, which can lead to permanent damage or fibrosis. Common signs of inflammation include redness, heat, swelling, and pain. The resolution process involves bleeding, clotting, epithelization, granulation formation, and wound contraction. Mobilization of defense cells helps limit pathogen spread and initiate tissue repair. Trauma response occurs over days, involving various stages of healing.

• Inflammation
• Tissue Damage
• Healing Process
• Defense Cells
• Trauma Response

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Uploaded on Feb 13, 2025 | 1 Views

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Presentation Transcript

1. Dr Rudra Pratap Pandey

2. initial physiological response to tissue damage, Causes irradiation, chemical, or microbial . Can be acute (lasting for a few days) or chronic (in response to an ongoing and unresolved insult). Inflammation can develop into permanent tissue damage or fibrosis. initial physiological response to tissue damage, Causes mechanical, thermal, electrical, irradiation, chemical, or microbial . acute (lasting for a few days) or chronic (in response to an ongoing and unresolved insult). Inflammation can develop into permanent tissue damage or fibrosis. mechanical, thermal, electrical,

3. Rubor or redness Calor or heat Tunor or swelling Dolor or pain Functio lissa (?)

4. RESOLUTION Bleeding .clotting .resolution Inflammation Epithelization Granulation formation Fibroblast secretion products collagen laying Wound contraction and remodelling UNTOWARD OUTCOME Fibrosis Abscess formation Chronic inflammation

5. Mobilization of defense cells Limiting the pathogen spread Killing the pathogens Initiation of tissue repair

6. TRAUMA RESPONSE DAYS