Insights into Hepatitis C Treatment Experience: Research Findings
Explore qualitative insights into living with and treating Hepatitis C, including the impact of comorbidities and alcohol use disorders. Understand the evolution of HCV therapy and the contemporary lived experience. Discover research aims, questions, and progress in understanding HCV treatment experience.
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Hepatitis C and its Treatment: Qualitative Insights into the Contemporary Lived Experience DAVID WHITELEY PHD RESEARCH STUDENT EDINBURGH NAPIER UNIVERSITY 4 0 1 0 3 8 1 3 @ L I V E . N A P I E R . A C . U K O R D W H I T E L E Y @ N H S . N E T
SCHWARZINER M et al. The confounding role of severe comorbidities and alcohol use disorders on prognosis in chronic hepatitis C virus infection: an analysis of the 2008-2012 French national hospital discharge database Abstract G16, 50thInternational Liver Congress, Vienna 2015 Alcohol plays a major and underappreciated role in the morbidity of those infected with HCV. I tried to give up drugs by drinking People with HCV 6 times more likely to have an alcohol use disorder than other hospitalised patients 46% of all liver-related events in people with HCV occurred in those with alcohol use disorders
A Brief History of Hepatitis C Evolution of HCV Therapy (Early 1990's to Present Day) 100% 90% 80% 70% SVR (Cure) Rate 60% 50% 40% 30% 20% 10% 0% IFN 24w IFN 48w IFN/RBV 24w IFN/RBV 48w PEG-IFN/RBV PEG-IFN/RBV + PI IFN-Free Regimes Early 1990 s Early 2000 s 2015
Research Aim & Questions AIM: To provide contemporary insights into hepatitis C and its treatment, within the context of a significantly improved cure. What is the lived experience of HCV, amongst those both accessing and not accessing HCV treatment services? 1) How adequate do theories of chronic illness remain to the contextual understanding of the experience of living with HCV? 2) What is the lived experience of individuals undergoing HCV treatment with recently licensed direct acting antivirals? 3)
Progress Individuals with HCV living in Edinburgh and the Lothians who fulfil the inclusion criteria maximum n = 40 Individuals not accessing specialised HCV secondary care maximum n = 10 Individuals accessing specialised HCV secondary care maximum n = 30 Interviews with purposively sampled participants End of participation for individuals not accessing specialised HCV care stream From individuals accessing care, recruitment for further post-treatment interviews maximum n = 10 Interview at end of treatment (EoT) n = 10 (- discontinuations) Interview any treatment discontinuations n = ? Interview 3-6/12 post-end of treatment n = 10 End of participation
