Liver Transplantation Report 2019/20 Insights
Explore key data and trends from the Annual Report on Liver Transplantation 2019/20. Discover statistics on active liver transplant lists, patient outcomes, and the total number of liver transplants. Gain valuable insights into the landscape of liver transplantation in the UK.
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Annual Report on Liver Transplantation 2019/20 SLIDE SET
Figure 2.1 Patients on the active liver transplant list at 31 March 700 611 600 577 553 549 530 500 510 466 492 432 Number 400 359 300 200 100 0 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020* Year Waiting list as at 29 February 2020 Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 2.2 Patients on the active liver transplant list at 29 February 2020 175 150 9 125 21 Number 100 75 128 7 104 50 57 25 49 39 30 22 0 Newcastle Leeds Cambridge Royal Free King's Birmingham Edinburgh College Transplant centre Adult Paediatric Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 2.3 Post-registration outcome for 1009 new elective liver only registrations made in the UK, 1 April 2017 - 31 March 2018 100 7 8 9 3 4 90 6 4 12 80 24 70 60 Percentage 50 82 40 76 66 30 20 10 0 6 months 1 year 2 years Time since listing Transplanted Still waiting Removed Died/Removed* *Removals due to condition deteriorating Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 2.4 Six month post-registration outcome for 1009 new elective liver only registrations made in the UK by centre, 1 April 2017 - 31 March 2018 100 6 15 7 6 7 8 11 3 3 . 3 3 90 6 22 20 21 80 26 24 30 26 70 60 Percentage 50 40 72 71 70 66 66 60 30 56 20 10 0 Newcastle Leeds Cambridge Royal Free King's College Birmingham Edinburgh Transplant centre Transplanted Still waiting Removed Died/Removed* *Removals due to condition deteriorating Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 2.5 Total number of liver transplants by donor type, 1 April 2010 - 31 March 2020 1100 701 782 817 912 882 918 980 1043 1003 942 N = 1 29 1 1000 3 21 31 1 3 18 4 900 2 28 36 200 188 38 2 170 209 800 5 31 153 38 206 177 4 No. of transplants 700 136 21 132 100 600 500 400 300 813 793 753 737 727 673 665 648 607 200 576 100 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year DBD DCD Living Domino Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 2.6 Total number of liver transplants by transplant centre and donor type, 1 April 2010 - 31 March 2020 Birmingham Cambridge Edinburgh King's College 280 245255254 247237231243233 234 240 229228 223207 206221221 207 200 182177 178 160 7686 85798791102117118 120 968895 96 97103103108 99 No. of transplants 81 80 65 40 0 Leeds Newcastle Royal Free 280 240 200 177 160 145 141 140 125132 119127 104104118124 114 120 10198 9888 76 80 63 3539 4148 47 3545 42382836 40 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year DBD DCD Living Domino Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 2.7 Liver transplants in the UK, 1 April 2010 31 March 2020 Liver Transplants 1 April 2010 - 31 March 2020 8980 Atypical transplants 317 (291 Living & 26 Domino) Deceased donor first liver only transplants 76811(DCD=1641) Deceased donor liver only re-transplants 821 Multi-organ transplants 161 Adult Paediatric 675 (DCD=33) 7005 (DCD=1608) Super-urgent2 630 (DCD=8) Elective Super-urgent2 119 (DCD=2) Elective 556 (DCD=31) 6375 (DCD=1600) 1 One patient refused consent for their data to be used in analysis and has been excluded from subsequent categorisation 2 Super-urgent registration categories were changed on 17 June 2015 to account for developments in treatment of patients with acute liver failure. Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 2.8 Total number of liver transplants by donor and transplant type, 1 April 2010 - 31 March 2020 1100 701 782 817 912 882 918 980 1043 1003 942 N = 30 4 1000 22 5 34 3 19 7 900 32 39 2 3 196 40 183 2 800 33 163 24 206 12 3 151 43 16 87 14 1 203 10 91 No. of transplants 175 700 25 133 86 92 15 98 25 131 11 100 600 81 19 68 83 12 57 51 500 400 300 702 690 651 631 619 200 569 569 565 531 513 100 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year First DBD liver only Re-transplant DBD liver only Multi-organ DBD First DCD liver only Re-transplant/Multi-organ DCD Living/Domino Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 2.9 Total number of liver transplants by transplant centre, donor type and transplant type, 1 April 2010 - 31 March 2020 Birmingham Cambridge Edinburgh King's College 280 245255254 247237231243233 234 229228 240 223207 206221221 207 200 182177 178 160 7686 85798791102117118 120 968895 96 97103103108 99 No. of transplants 81 80 65 40 0 Leeds Newcastle Royal Free 280 240 200 177 160 119127145 9888104104118124141 140 125132 10198114 120 6376 80 3539 41483545 42382836 47 40 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year First DBD liver only Re-transplant DBD liver only First DCD liver only Multi-organ DBD Re-transplant/Multi-organ DCD Living/Domino Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 2.10 Comparison of liver registration rates (pmp) with transplant rates (pmp) by recipient country/NHS region of residence Registrations Transplants Liver registration rates Liver transplant rates Low rate (13.60-<16.90 pmp) Low rate (10.7-<12.4 pmp) Low-Medium rate (16.90-<18.70 pmp) Low-Medium rate (12.4-<14.3 pmp) Medium-High rate (18.70-<19.40 pmp) Medium-High rate (14.3-<15.9 pmp) 19.1 12.5 High rate (19.40-20.20 pmp) High rate (15.9-16.5 pmp) 20.2 16.5 16.6 12.4 17.0 11.7 18.7 15.9 19.4 13.7 19.6 14.9 16.9 15.9 13.6 10.7 18.7 15.9 Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.1 Deceased donor first liver only transplants in the UK in adult recipients 1 April 2010 - 31 March 2020 900 535 595 635 701 690 704 761 828 803 753 N = 800 74 68 55 64 700 61 71 69 54 600 No. of transplants 56 58 500 400 754 735 706 689 643 630 621 300 581 539 477 200 100 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year Elective Super-urgent* *Super-urgent registration categories were changed on 17 June 2015 to account for developments in treatment of patients with acute liver failure Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.2 Deceased donor first liver only transplants in the UK in adult recipients, 1 April 2010 - 31 March 2020 Birmingham Cambridge Edinburgh King's College 210 189 185 181 178 176 174 172 172 171 165 180 161 160 157 153 143 140 137 133 133 150 112 104 104 120 88 8886 879296 90 86 8776 81 90 77 72 72 71 68 69 No. of transplants 55 60 30 0 Leeds Newcastle Royal Free 210 180 134 150 133 119 114 106 106 120 102 97 91 89 88 87 84 83 90 79 79 70 64 56 60 41 33 3436393038 37342833 30 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year Elective Super-urgent* *Super-urgent registration categories were changed on 17 June 2015 to account for developments in treatment of patients with acute liver failure Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.3 Boxplot of cold ischaemia time in all adult first deceased donor liver transplants, by donor type and financial year 1 April 2010 - 31 March 2020 DBD DCD 25 20 Cold ischaemia time (hours) 15 10 5 0 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 Year Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.4 Boxplot of cold ischaemia time in all adult first deceased donor liver transplants, by donor type and transplant centre 1 April 2019 - 31 March 2020 DBD DCD 25 20 Cold ischaemia time (hours) 15 10 5 0 Birmingham Cambridge Edinburgh King's Leeds Newcastle Royal Free Birmingham Cambridge Edinburgh King's Leeds Newcastle Royal Free College College Transplant centre Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.5 Boxplot of cold ischaemia time in all adult first DBD donor liver transplants, 1 April 2010 - 31 March 2020 Birmingham Cambridge Edinburgh King's College 25 20 15 10 Cold ischaemia time (hours) 5 0 Leeds Newcastle Royal Free 25 20 15 10 5 0 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 Year Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.6 Boxplot of cold ischaemia time in all adult first DCD donor liver transplants, 1 April 2010 - 31 March 2020 Birmingham Cambridge Edinburgh King's College 25 20 15 10 Cold ischaemia time (hours) 5 0 Leeds Newcastle Royal Free 25 20 15 10 5 0 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 Year Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.9 Post-registration outcome for 928 new elective adult liver only registrations made in the UK, 1 April 2017 - 31 March 2018 100 7 9 9 3 90 4 6 4 12 80 24 70 60 Percentage 50 81 40 75 66 30 20 10 0 6 months 1 year 2 years Time since listing Transplanted Still waiting Removed Died/Removed* *Removals due to condition deteriorating Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.10 Six month post-registration outcome for 928 new elective adult liver only registrations made in the UK by centre, 1 April 2017 - 31 March 2018 100 15 6 6 7 8 8 11 3 3 - 3 2 90 6 22 20 21 80 26 22 30 26 70 60 Percentage 50 40 72 71 70 67 66 60 30 56 20 10 0 Newcastle Leeds Cambridge Royal Free King's College Birmingham Edinburgh Transplant centre Transplanted Still waiting Removed Died/Removed* *Removals due to condition deteriorating Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.11 Named adult elective liver offer decline rates that resulted in a liver only first transplant from DBD donors, 1 April 2018 and 31 March 2020 100 80 Newcastle Offer decline rate (%) King's College Cambridge 60 Leeds Royal Free Edinburgh Birmingham 40 20 99.8% Upper CL 95% Lower CL 95% Upper CL 99.8% Lower CL National rate Centre rate 0 0 50 100 150 200 250 300 350 400 450 500 Centre specific offers Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.12 Adult elective liver offer decline rates that resulted in a liver only first transplant from DCD donors, 1 April 2018 and 31 March 2020 100 Newcastle 80 Edinburgh Offer decline rate (%) 60 Leeds Birmingham 40 Cambridge Royal Free King's College 20 99.8% Upper CL 95% Lower CL 95% Upper CL 99.8% Lower CL National rate Centre rate 0 0 10 20 30 40 50 60 70 80 90 100 110 120 Centre specific offers Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.13 Adult elective liver only transplants by donor type, 1 April 2010 - 31 March 2020 900 489 555 592 648 640 663 719 764 741 696 N = 800 10 6 13 7 700 20 189 18 19 178 161 201 11 600 No. of transplants 16 149 197 170 131 500 12 128 96 400 300 565 557 528 505 481 450 451 446 411 200 381 100 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year DBD DCD Living (including domino) Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.14 Adult elective liver only transplants by donor type and centre, 1 April 2010 - 31 March 2020 Birmingham Cambridge Edinburgh King's College 200 180 170170166171163 151160168 150152156 156 160 141145137 140 132128 116125 120 99 879498 100 687684 82858893 80 80 77 80 657166 6568 65 No. of transplants 60 50 40 20 0 Leeds Newcastle Royal Free 200 180 160 140 124 120 120 107 105 101 97 97 100 85 87 86 7885 79 78 77 80 69 64 61 60 52 38 2731 33 322632 34312428 40 20 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year DBD DCD Living (including domino) *Excludes 16 and 5 living liver transplants at London Bridge Hospital and Cromwell Hospital, respectively Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.15 Risk-adjusted 1 year patient survival rates for adult elective deceased donor first liver transplants, 1 April 2015 - 31 March 2019 100 Cambridge King's College Edinburgh Birmingham Royal Free Newcastle Leeds 90 % 1 year patient survival 80 70 60 99.8% Upper CL Risk-adjusted centre rate 95% Upper CL 95% Lower CL National rate 99.8% Lower CL 50 0 100 200 300 400 500 600 700 Number of transplants Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.16 Risk-adjusted 5 year patient survival rates for adult elective deceased donor first liver transplants, 1 April 2011 - 31 March 2015 100 Royal Free 90 Cambridge King's College % 5 year patient survival Edinburgh Birmingham Leeds 80 Newcastle 70 60 99.8% Upper CL Risk-adjusted centre rate 95% Upper CL 95% Lower CL National rate 99.8% Lower CL 50 0 100 200 300 400 500 600 Number of transplants Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.17 Risk-adjusted 1 year patient survival rate from time of listing for adult* elective first liver registrations, 1 January 2008 - 31 December 2019 95 % 1 year patient survival from listing Edinburgh King's College Cambridge Newcastle 85 Royal Free Leeds Birmingham 75 99.8% Upper CL 95% Lower CL 95% Upper CL 99.8% Lower CL National rate Risk-adjusted centre rate 65 0 500 1000 1500 2000 2500 Number of patients * In this analysis, adult patients are defined as 18 years old and older. Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.18 Risk-adjusted 5 year patient survival rate from time of listing for adult* elective first liver registrations, 1 January 2008 - 31 December 2019 85 Edinburgh % 5 year patient survival from listing King's College Cambridge 75 Newcastle Royal Free Birmingham Leeds 65 55 99.8% Upper CL 95% Lower CL 95% Upper CL 99.8% Lower CL National rate Risk-adjusted centre rate 45 0 500 1000 1500 2000 2500 Number of patients * In this analysis, adult patients are defined as 18 years old and older. Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.19 Adult super-urgent* liver only transplants by donor type, 1 April 2010 - 31 March 2020 125 58 57 54 71 69 61 55 74 68 64 N = 100 No. of transplants 75 1 1 2 2 2 1 50 74 71 68 67 62 59 56 56 55 54 25 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year DBD DCD Living *Super-urgent registration categories were changed on 17 June 2015 to account for developments in treatment of patients with acute liver failure Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.20 Adult super-urgent* liver only transplants by centre, 1 April 2010 - 31 March 2020 Birmingham Cambridge Edinburgh King's College 30 21 1918 20 18 1817 1817 17 16 15 15 13 1213 12 12 11 10 10 9 9 10 No. of transplants 8 8 8 6 6 6 6 5 5 5 4 4 4 4 3 3 3 2 0 Leeds Newcastle Royal Free 30 20 14 111213 111213 1112 11 10 8 7 7 7 7 6 6 6 6 5 5 4 4 4 4 3 3 3 3 3 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year DBD DCD Living *Super-urgent registration categories were changed on 17 June 2015 to account for developments in treatment of patients with acute liver failure Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.21 Risk-adjusted 1 year patient survival rates for adult super-urgent deceased donor first liver transplants, 1 April 2015 - 31 March 2019 100 Birmingham Cambridge Leeds 90 King's College Royal Free % 1 year patient survival 80 Newcastle Edinburgh 70 60 50 99.8% Upper CL Risk-adjusted centre rate 95% Upper CL 95% Lower CL National rate 99.8% Lower CL 40 0 25 50 75 Number of transplants Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 3.22 Risk-adjusted 5 year patient survival rates for adult super-urgent deceased donor first liver transplants, 1 April 2011 - 31 March 2015 100 90 Edinburgh Cambridge King's College % 5 year patient survival Birmingham 80 Leeds Royal Free Newcastle 70 60 50 99.8% Upper CL Risk-adjusted centre rate 95% Upper CL 95% Lower CL National rate 99.8% Lower CL 40 0 25 50 75 Number of transplants Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 4.1 Deceased donor liver only transplants in paediatric recipients in the UK, 1 April 2010 - 31 March 2020 100 77 67 67 69 54 64 76 70 70 61 N = 90 80 9 70 21 No. of transplants 9 8 15 11 13 60 9 12 50 12 40 67 61 61 30 56 56 55 55 54 49 42 20 10 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year Elective Super-urgent* *Super-urgent registration categories were changed on 17 June 2015 to account for developments in treatment of patients with acute liver failure Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 4.2 Deceased donor liver only transplants in paediatric recipients* in the UK, Figure 4.2 Deceased donor liver only transplants in paediatric recipients* in the UK, 1 April 2009 - 31 March 2019 1 April 2010 - 31 March 2020 B6313 Birmingham King's College G1401 M1202 Leeds 50 50 No. of transplants No. of transplants 41 41 37 39 39 40 40 37 35 36 36 35 35 35 32 32 32 31 31 31 31 30 30 28 28 26 23 23 23 22 22 21 21 20 20 20 20 15 19 19 20 20 18 18 13 17 17 13 17 16 16 15 15 15 13 13 12 11 11 11 9 9 9 9 10 10 5 5 0 0 2009-2010 2010-2011 2010-2011 2011-2012 2011-2012 2012-2013 2013-2014 2012-2013 2014-2015 2013-2014 2015-2016 2014-2015 2015-2016 2016-2017 2017-2018 2016-2017 2018-2019 2017-2018 2018-2019 2019-2020 2010-2011 2009-2010 2010-2011 2011-2012 2011-2012 2012-2013 2012-2013 2013-2014 2013-2014 2014-2015 2014-2015 2015-2016 2015-2016 2016-2017 2016-2017 2017-2018 2017-2018 2018-2019 2019-2020 2018-2019 2009-2010 2010-2011 2010-2011 2011-2012 2012-2013 2011-2012 2013-2014 2012-2013 2014-2015 2013-2014 2015-2016 2014-2015 2016-2017 2015-2016 2017-2018 2016-2017 2018-2019 2017-2018 2018-2019 2019-2020 Financial Year Financial Year Elective Elective Super-urgent** Super-urgent** *Excludes four super-urgent paediatric patients who were transplanted at non-paediatric centre *Excludes four super-urgent paediatric patients who were transplanted at non-paediatric centre **Super-urgent registration categories were changed on 17 June 2015 to account for developments **Super-urgent registration categories were changed on 17 June 2015 to account for developments in treatment of patients with acute liver failure in treatment of patients with acute liver failure Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 4.3 Boxplot of cold ischaemia time in all paediatric first deceased donor liver transplants, by donor type and financial year 1 April 2010 - 31 March 2020 DBD DCD 25 20 Cold ischaemia time (hours) 15 10 5 0 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 Year Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 4.5 Boxplot of cold ischaemia time in all paediatric first DBD donor liver transplants, 1 April 2010 - 31 March 2020 Birmingham King's College Leeds 20 15 Cold ischaemia time (hours) 10 5 0 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020 Year Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 4.6 Boxplot of cold ischaemia time in all paediatric first DCD donor liver transplants, 1 April 2010 - 31 March 2020 Birmingham King's College 20 15 Cold ischaemia time (hours) 10 5 0 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 Year Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 4.9 Post-registration outcome for 82 new elective paediatric liver only registrations made in the UK, 1 April 2017 - 31 March 2018 100 4 4 4 4 4 4 4 90 11 80 32 70 60 Percentage 50 89 82 40 61 30 20 10 0 6 months 1 year 2 years Time since listing Transplanted Still waiting Removed Died/Removed* *Removals due to condition deteriorating Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 4.10 Six month post-registration outcome for 82 new elective paediatric liver only registrations made in the UK by centre, 1 April 2017 - 31 March 2018 0 50 100 6 7 2 90 24 80 38 32 70 60 Percentage 50 40 71 59 30 57 20 10 0 Birmingham King's College Leeds Transplant centre Transplanted Still waiting Removed Died/Removed* *Removals due to condition deteriorating Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
Figure 4.11 Paediatric elective liver only transplants, 1 April 2010 - 31 March 2020 100 69 77 77 74 60 71 86 77 70 60 N = 80 19 16 13 21 23 5 No. of transplants 16 13 15 2 60 7 2 2 11 3 4 3 18 3 40 62 59 54 54 54 52 51 51 49 20 39 0 2010-2011 2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 Financial Year DBD DCD Living Source: Annual Report for Liver Transplantation 2014/15, NHS Blood and Transplant Source: Annual Report on Liver Transplantation 2019/20, NHS Blood and Transplant
