
Lymphoid Leukosis in Poultry: Causes, Symptoms, and Prevention
Learn about Lymphoid Leukosis (LL), a neoplastic disease affecting adult chickens, its etiology, clinical signs, post-mortem lesions, differential diagnosis, and prevention strategies. Identify important aspects such as incubation period, method of spread, and diagnostic methods.
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poultry diseases 2 fourth stage chapter three Viral Diseases- lecture 7 part 2 Lymphoid leukosis (LL) Dr.HarithAbdulla Department of Pathology and Poultry Disease College of veterinary medicine university of basrah University of Basrah- College of veterinary medicine- Department of Pathology and Poultry Disease
Lymphoid leukosis (LL) Lymphoid leukosis is a bursal dependent neoplastic disease of adult chickens ( over 14 16 weeks of age). LL characteristically produces lymphoid tumors, liver and spleen, other visceral organs such as ovary and lungs may also affected . O Etiology: Etiology: Small RNA leukosis / sarcoma virus . O Incubation period Incubation period : : 14 30 weeks . O Method Method of spread of spread :- 1. Transovarian . 2. Lateral transmission . 3. Blood sucking parasites . particularly in
O Clinical signs: Clinical signs: 1 1.The disease is chronic in nature ,but affected birds may .The disease is chronic in nature ,but affected birds may die without signs. die without signs. 2.Pale shriveled combs . 3. Progressive emaciation and diarrhea. 4.Total loss may approach 20% . 5.Losses most severe after onset of egg production 6.Abdominal enlargement. 7.Blood blisters may occur in the skin ,their rupture causing hemorrhage.
OPost Post mortem lesions : mortem lesions : 1. Hepatomegaly : The liver is filling the entire abdominal cavity ,(Big Liver Disease). It is firm, fibrous, and gritty. 2.Enlarged bursa of Fabricius . 3.Tumors on the mesentery and other abdominal viscera. 4.Tumors are soft, smooth, and glistening. 5.Tumors may be nodular ,miliary ,diffuse or combination of these forms. 6.Sometime tumors in the bones .
Differential Differential Diagnosis: 1. Marek s disease(Visceral form) . 2. Avian tuberculosis . 3. Coligranuloma. 4. Histomoniasis {Black Head Disease} . ODiagnosis Diagnosis : : 1. Signs . 2. Post mortem lesions:- A. Bursa of Fabricius enlargement . B. Lack of nerve involvement . 3. Histopathology . 4. ELISA. Diagnosis:
Prevention: 1. Elimination of the virus from breeder hens . A. Test and slaughter . B. Virus is spread to the progeny . 2 . Genetic resistant birds. 3 . Vaccination.
O Mareks disease 1. Age : Young and adult . Nerves: Are affected . Skin : Is affected . Bursa of Fabricius is mainly not involved. O L.L 1.Age:Over 14 16 weeks. 2.Nerves: Not involved . 3.Skin: Is not affected . 4.Bursa of Fabricius:Is the target organ. 2. 3. 4.