Mediastinal Diseases: Anatomy, Pathology, and Clinical Presentation
Explore the world of mediastinal diseases with a focus on anatomy, pathology, clinical presentation, and investigative methods. Learn about diverse conditions affecting the mediastinum, such as neoplastic growths, mediastinitis, and pneumomediastinum. Uncover the most common mediastinal diseases including those involving the thymus, thyroid, teratoma, lymphoma, and congenital cysts. Clinical presentations may range from asymptomatic cases to symptoms like Hoarseness, SVC syndrome, and more. Delve into diagnostic investigations like imaging studies, laboratory tests, and histopathological procedures for a comprehensive understanding of managing mediastinal diseases.
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Presentation Transcript
MEDIASTINAL DISEASES Omar Mangoush
Anatomy Pathology Clinical presentation Investigations
Mediastinal Pathology None neoplastic Mediastinitis Pneumomediastinum Most Common: Thymus Thyroid Teratoma Lymphoma Congenital Cysts Hernias Acquired Benign Malignant
Clinical Presentation Most asymptomatic, Incidental finding Horner s Synd Sympathetic Airway compression pneumonia SVC synd Haemoptysis Dysphagia Constitutional Paralysis Associated with systemic disease: Mythenia, thyrotoxicosis, Cushing s and parathyrodism Hoarseness RLN Elevated HD phrenic
Investigations: Imaging MRI US PET
Investigations: laboratory TFT PTH Urine metanephrine and catecholamines AFP & Beta HCG
Investigations: histo-pathology FNA / Tru-cut CT guided EUS guided Mediastinoscope Mediastinostomy VATs Thoracotomy
