Modelling Individual and Population Dynamics for Chemical Risk Assessment
"Explore tools based on Dynamic Energy Budget for assessing risks of chemical mixtures on individuals and populations. Literature review includes keywords like DEB, Ecotoxicology, and Population Dynamics."
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Presentation Transcript
Modelling individual and population Modelling individual and population dynamics in application to risk dynamics in application to risk assessment of chemical mixtures assessment of chemical mixtures Gon alo M. Marques Jan Baas, Starrlight Augustine and Jean-Lou Dorne Akvaplan goncalo.marques@tecnico.ulisboa.pt
Summary Summary The job: Tools for ERA based on DEB for 1. individuals and populations 2. single compounds and mixtures in R Akvaplan
Summary Summary R code R code Literature review Database individual model population model Akvaplan
Literature Literature review review Examples of keywords used: DEB Dynamic Energy Budget Mixtures Ecotoxicology Modelling Mortality Growth Reproduction Population Dynamics Individual based modelling Akvaplan
Literature Literature review review Examples of keywords used: DEB Dynamic Energy Budget Mixtures Ecotoxicology Modelling Mortality Growth Reproduction Population Dynamics Individual based modelling T. Jager et al., Debkiss or the quest for the simplest generic model of animal life history. Journal of Theoretical Biology, 328:9-18, 2013 K. Lika et al., The `covariation method' for estimating the parameters of the standard Dynamic Energy Budget model I: philosophy and approach. J. Sea Res., 66:270-277, 2011 Akvaplan
Literature Literature review review Examples of keywords used: DEB Dynamic Energy Budget Mixtures Ecotoxicology Modelling Mortality Growth Reproduction Population Dynamics Individual based modelling Refs General DEB modelling 18 Effects of mixtures 7 Population dynamics 15 Akvaplan
DEB DEB Akvaplan
DEBecotox DEBecotox d database atabase Akvaplan
DEBecotox DEBecotox database database (1 ?) (1 + ?) par /(1 + ?) NEC conc Akvaplan
DEB DEB MoA MoA Akvaplan
DEB DEB MoA MoA Assimilation Maintenance Growth Reproduction Survival Akvaplan
DEB DEB MoA MoA Assimilation Maintenance Growth Reproduction Survival Akvaplan
Mixtures Mixtures Independent action Assimilation Maintenance Growth Reproduction Survival Akvaplan
Mixtures Mixtures Similar action Assimilation Maintenance Growth Reproduction Survival Akvaplan
Mixtures Mixtures Quantitative Structure Activity Relationships (QSAR) Body-size scaling relationships Akvaplan
DEBecotox DEBecotox R package R package Add-my-Pet code structure Akvaplan
DEBecotox DEBecotox R package R package Akvaplan
DEBecotox DEBecotox R package R package Akvaplan
DEBecotox DEBecotox R package R package Typified model DEB MoA Group of action Akvaplan
DEBecotox DEBecotox R package R package Typified model DEB MoA Group of action Akvaplan
DEBecotox DEBecotox R package R package Akvaplan
Future Future developments developments R code R code Literature review Database individual model population model Akvaplan
Thank you! EFSA, Nov 2015 Akvaplan
