Natural History of Cervical Carcinogenesis and Cancer Prevention

Natural History of Cervical Carcinogenesis and Cancer Prevention
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Natural History of Cervical Carcinogenesis explores the progression from HPV infection to invasion, covering HPV-infected cervix, normal cervix, precancerous stages, and cervical cancer. Prevention methods like Pap smear screening, colposcopy, and follow-ups are crucial in early detection and treatment. Dysplasia, both low grade and high grade, are key indicators in assessing the risk of progression towards cancer.

  • Cervical Carcinogenesis
  • Cancer Prevention
  • HPV Infection
  • Pap Smear Screening
  • Dysplasia

Uploaded on Mar 11, 2025 | 0 Views


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  1. Case 4

  2. Natural History of Cervical Carcinogenesis HPV Infection Progression Invasion HPV- Infected Cervix Normal Cervix Cervical Cancer Precancer Clearance Regression Mild Cytologic and/or Histologic Abnormalities Schiffman M, Kjaer SK. J Natl Cancer Inst Monogr. 2003;(31):14-19.

  3. Cervical Cancer Prevention Pap smear screening (HPV testing) Abnormal Pap or high-risk HPV Colposcopy Negative or CIN I Follow-up Pap or HPV testing 6 months - 1 year CIN II-III LEEP/cone Follow-up Pap 6 months

  4. Low Grade Dysplasia

  5. High Grade Dysplasia punctations abnormal vessels mosaic pattern

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