Pathology of Diabetes Mellitus: Understanding the Complications

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Diabetes mellitus is a metabolic disorder characterized by inadequate insulin action, leading to various complications affecting different organs. Learn about the pathology, definition, measurement, insulitis, metabolic actions of insulin, pathogenesis of type 2 diabetes, and complications such as atheroma, hypertension, diabetic nephropathy, retinopathy, and neuropathy.

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Uploaded on Mar 11, 2025 | 0 Views

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ENDOCRINE BLOCK Lecture 1 and 2: Lecture 1 and 2: Pathology of Diabetes Pathology of Diabetes Mellitus Mellitus

Diabetes mellitus is an extremely common metabolic disorder, which is increasing in prevalence. It is known as a syndrome of inadequate insulin action . The type 1 condition is insulin dependent. The type 2 condition is non-insulin dependent. Eye, renal, vascular and neurological complications are commonplace.

Definition Diabetes is defined clinically as either a fasting plasma glucose level 7.8 mmol/L (140 mg/dL) or 2-hour plasma glucose 11 mmol/L (200 mg/dL) postprandial