Postoperative Oxygen Therapy in Patients with OSA: Randomized Trial
A study by Liao et al. in Chest 2017 investigated the impact of supplemental oxygen on oxygen saturation, sleep respiratory effects, and CO2 levels in untreated obstructive sleep apnea (OSA) patients. The trial involved 195 consented participants, with preoperative polysomnography revealing 123 OSA patients and 61 controls. Changes in oxygen saturation parameters were noted postoperatively, with significant findings observed in per-protocol analyses. Additionally, alterations in apnea-hypopnea index (AHI) from preoperative to postoperative night-3 were examined, highlighting differences between oxygen and no-oxygen groups. Notably, 14 patients exhibited elevated partial pressure of transcutaneous carbon dioxide (Ptc.CO2) levels postoperatively, indicating potential respiratory depression.
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Presentation Transcript
Postoperative O2 Therapy in Patients with OSA: A Randomized Controlled Trial Liao P et al. Chest 2017 Screened: 722 To investigate the effect of supplemental O2 on oxygen saturation, sleep respiratory effects and CO2 levels in untreated OSA. Consented:195 Preoperative PSG: 170 obstructive sleep apnea pt: 123 Control: 61 Oxygen: 62
Changes in parameters measuring O2 saturation (posto night 3, per-protocol analysis) Liao P et al. Chest 2017 *: p<0.05 vs No-Oxygen
AHI change from preop to postop night-3 in two groups, per-protocol analysis Liao P et al. Chest 2017
Postoperative O2 Therapy in Patients with OSA. Liao P et al. Chest 2017 14 Patients had high Ptc CO2 postoperative nights One pt. Ptc CO2 96 mmHg 7 pt. Ptc CO2 >60 mmHg 14 patients had worrying high CO2 indicating respiratory depression
