Potassium Permanganate: Properties and Pharmaceutical Applications
Potassium permanganate, with formula KMnO4, exhibits unique physical and chemical properties. It is commonly known as Condy's crystals and is used in pharmaceutical applications for its oxidizing, antibacterial, and disinfectant properties. Learn about its preparation, physical and chemical properties, as well as its use in treating skin conditions and as a strong oxidizing agent in chemical reactions.
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Presentation Transcript
Introduction Physical properties Chemical properties Pharmaceutical application Chemical principle Procedure Calculation
INTRODUCTION : Potassium permanganate has formula (KMnO4) with M.wt = 158.03gm/mol. sometimes called by its common name Condy's crystals. Potassium permanganate is prepare by heating potassium hydroxide with manganese dioxide in the presence of air or an oxidizing agent . 2KOH + MnO2+1/2O2 The K2MnO4converts into KMnO4by reacts with ( CO2 , Cl2and H2O ) 3K2MnO4+ 2CO2 2KMnO4+ MnO2+ 2K2CO3 The potassium manganese reacts with Cl2converted in to KMnO4 2K2MnO4+ Cl2 2KMnO4+ 2KCl The potassium manganese reacts with H2O converted in to KMnO4 2K2MnO4+ 2H2O 2KMnO4+ 2KOH + H2 K2MnO4+ H2O
Physical properties 1- Odorless dark purple crystals . 2- The M.wt is158.03gm/mol . 3- Soluble in water (hot water) decompose by alcohol . 4- Stored in dark place it sensitive to light . 5- Luster by reflected light
Chemical properties 1- It is secondary standard solution because it has low eq.wt M.wt of KMnO4= 158.3 ?? ??? Eq.wt of KMnO4= 158.3 5? 2- It is self-indicator. 3- It is unstable in light. 2 KMnO4 4- It is react with potassium iodide (KI) and liberate iodate (KIO3) in neutral and basic medium. 4KMnO4+ 2KI + 2H2O 4MnO2 + 2KIO3+ 4KOH And in acidic medium it is liberate (I2) like 2KMnO4+10KI + 8H2SO4 2MnSO4 + 6K2SO4+ 5I2+ 8H2 = 31.16 K2MnO4+ MnO2(s) + O2
5- Potassium permanganate is strong oxidizing agent it will oxidize any organic matter , It is used as a qualitative test for the presence of double or triple bonds in molecule . CH3(CH2)17CH=CH2+ 2 KMnO4+ 3 H2SO4 CH3(CH2)17COOH + CO2+4 H2O + K2SO4+ 2 MnSO4
Pharmaceutical application 1- Oxidized proteins and bio organic substance. 2- Crystals of potassium permanganate are dissolved in warm water to get a purple solution which is very useful for treatment of various skin conditions like eczema, and dermatitis . 3- Anti-bacterial . 4- deodorant properties . 5- disinfectant properties so it used to cleaner a ulcer and abscess . .
Potassium permanganate is a strong oxidizing agent , So the assay of it depended on Oxidation Reduction Reaction ( Redox Reaction),Chemical reactions involve the transfer of electrons between species , Oxidation is the loss of electrons or an increase in oxidation state by a molecule, atom, or ion. Reduction is the gain of electrons or a decrease in oxidation state by a molecule, atom, or ion. Permanganate is not primary standard solution , There for many primary standard have been proposed for standardization of permanganate , the include H2C2O4 , Na2C2O4 , As2O3, K4[Fe (CN)6] . 5H2C2O4+2KMnO4+3H2SO4 2MnSO4+K2SO4 +8H2O +10CO2 Mn+7+ 5e- (C+32 O4)+2 Mn+2(Reduction process ) 2C+4O2+ 2e- (Oxidation reaction)
1- Fill the burette with KMnO4 solution . 2-Take (5ml) of (0.1N) Na2C2O4in conical flask and add to it (7.5ml) of diluted H2S04. 3-Heat the flask to (800C) . 4-Titrate with KMnO4solution until a first drop gives a pink color .
1- Calculate the normality of KMnO4solution . 2- Calculate the quantity of KMnO4in your sample .
