Protein Synthesis
Delve into the intricate processes of transcription, translation, and mRNA editing essential to the synthesis of proteins. Explore detailed animations, DNA base pairing rules, and the distinction between introns and exons, providing a thorough understanding of biological mechanisms.
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Presentation Transcript
Animation of the Flow of Information http://www.wiley.com/college/boyer/0470003790/animations/central_dogma/central_dogma.htm (skip to the end) Crick on central dogma http://www.dnalc.org/view/15473-The-Central-Dogma-transcription-and- translation-James-Watson.html
Animations of Transcription http://www.stolaf.edu/people/giannini/flashanimat/molgenetics/transcription.swf (simple and to the point) http://www-class.unl.edu/biochem/gp2/m_biology/animation/gene/gene_a2.html (little more complex) http://www.dnatube.com/video/5734/Central-dogma-of-transcription (virtual)
How Humans transcribe Open the DNA, read the template strand and follow the RNA base pairing rules DNA Complementary Strand ATG TGG CGA mRNA AUG UGG CGA DNA Template Strand TAC ACC GCT
EDITTING Once mRNA is formed it is edited and sent out to the ribosome The mRNA transcript has a cap and a tail added. The mRNA transcript has the region coding for introns removed. DNA is composed of both introns and exons. Exons are segments of DNA that are expressed as genes. Introns are junk DNA. They are not expressed and must be removed before the mRNA leaves the nucleus.
Animation about mRNA editing http://www.dnatube.com/video/5930/MRna-Splicing-Video (splicing analogy with text)
Translation Animations http://www.stolaf.edu/people/giannini/flashanimat/molgenetics/translation.swf (simple and to the point) http://www-class.unl.edu/biochem/gp2/m_biology/animation/gene/gene_a3.html (little more complex) http://www.dnatube.com/video/5934/Basic-explanation-of-mRNA-Translation (virtual)
How humans translate Look up each mRNA codon on the table to determine the amino acid sequence. mRNA AUG CCA GAG UAU UGA Amino acids
Review of the flow of information Animation http://www.johnkyrk.com/er.html
Review Try it for yourself: http://www.pbs.org/wgbh/aso/tryit/dna/shockwave.html (replication & protein synthesis) Very detailed 10 minute video of protein synthesis www.youtube.com/watch?v=J3HVVi2k2No
BINGO with the genetic code Remember This is mRNA AUG = start codon
Structure letter A B C D E F Name of the structure Function/Purpose of the structure