Release of Growth Factors from CGF: Insights and Trends
This study presents findings on the release of growth factors IGF-1 and BMP-2 from CGF, both alone and in combination with TCP. The results show distinct patterns in the release of these factors over different time points, shedding light on potential applications in regenerative medicine and tissue engineering.
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Presentation Transcript
RELEASE OF SOME GROWTH FACTORS FROM CGF-TCP A part of the results of this study referred to the relase of growth factors from CGF alone are enclosed in a submitted paper (Borsani et al. 2015)
Comments: IGF-1 and BMP-2 showed different release . In particular with round-up and TCP: -The release of IGF-1 is lower at all time points. -The release of BMP-2 increases (very much) at all time point.
BMP-2 in vitro release % CGF without round up % CGF round up % CGF + TCP round up 5hours 2,202777778 1239,0625 1438,125 1day 30,32652778 1310,494792 1692,708333 3days 43,535 1650,729167 1849,791667 6days 33,27916667 1401,96875 1776,666667 8days 82,65652778 1118,541667 1768,541667
BMP-2 in vitro release 2000 1800 1600 1400 1200 % of release % CGF without round up 1000 % CGF round up % CGF + TCP round up 800 600 400 200 0 5hours 1day 3days 6days 8days Experimental times
IGF-1 in vitro release % media CGF without round up % media CGF + TCP round up % media CGF round up 5hours 97,01182059 48,97824377 120,4469067 1day 91,01200349 44,86921756 80,56388729 3days 98,41912626 45,21916356 85,52914548 6days 132,53937 59,95966291 80,69254391 8days 129,6602149 59,86525557 91,98504587
IGF-1 in vitro release 140 120 100 % of release 80 % CGF without round up % CGF round up % CGF + TCP round up 60 40 20 0 5hours 1day 3days 6days 8days Experimental times
