Schizophrenia: Symptoms, Phases, and Prognosis

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Explore the definition of schizophrenia, its acute and chronic phases, diagnosis, prognosis, epidemiology, factors influencing prognosis, and etiology. Learn about the symptoms, behaviors, and challenges associated with this mental health condition.

  • Schizophrenia
  • Mental health
  • Symptoms
  • Prognosis
  • Etiology

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  1. SCHIZOPHRENIA SCHIZOPHRENIA DEFINITION DEFINITION C/F prodrome social contact, Acute phase Chronic phase drive

  2. acute phase acute phase appearance and behavior withdrawal,perplexity,violance, posturing Affect suspiciosness,bewilderment, incongruent Speech ununderstandable ,irrelivant,incoherent

  3. Acute phase Thought Form, lack of association knight moves neologisms derailment content, delusions primary secondary

  4. Acute phase Perception auditory hallucination,commentory,3rd thought echo Self experience Thought interference Broadcasting Withdrwal Insertion Passivity, made action, impulse, feeling, somatic sensation

  5. Chronic phase Chronic phase Mainly negative symptoms Lack of volition Poverty of affect Poverty of speech Ventricular enlargement Poor response to narcoleptics Poor prognosis

  6. Epidemiology Epidemiology 25-40 men=women 1%

  7. Diagnosis Diagnosis Schnieder`s first rank ICD 1O DSM IV Subtypes paranoid disorgenized catatonic

  8. DDx DDx Depression Mania Delusional disorder Drugs Medical conditions

  9. Prognosis Prognosis 20% recover 35% relapsing no symptoms between 20% relapsing symptoms between 20% down since start 10% suicide

  10. Factors of prognosis Factors of prognosis Onset Event Family history Premorbid personality Affective symptoms EE IQ Ventricle size Positive or negative culture

  11. Etiology Etiology genetic factors 60 % no family history one parent two parents mono twines di twins

  12. Etiology Etiology environmental factors Season of birth, Influenza, Birth trauma Biological dopamine hypothesis brain changes

  13. Etiology Etiology social factors shizophrenic mother schism skew double bind social class

  14. Management Management Admission Violent patient Drugs

  15. Phenothiazines Aliphatic chlorpromazine ( largactile) Piperdines thioridazine ( melleril) Piprazines trifluorperazine(stelazine) , fluphenazine N/B fluphenazine decanoate (modecate) Actions Antidopaminergic anticholenergic antiserotoninergic, antiadrenergic

  16. Management SE early hrs intermediate days late months Butyrophenones, haloparidol Atypicals resperdone clozapine , olanzapines ECT

  17. Management of chronic phase Management of chronic phase Relapse prevention, atypicals Rehabilitation Services

  18. Relapse prevention Relapse prevention Drugs EE Events Social asylum vs. community

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