
Steroids for Muscle Growth and Hormonal Effects
Explore the impact of steroids on muscle growth, hormone mechanisms, testosterone levels, risks of abuse, and side effects in men and women. Learn about non-steroidal muscle growth enhancement and myostatin inhibition for optimizing performance.
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Presentation Transcript
Steroids & Muscle Growth JENNIFER SCHRANDT JENNIFER.SCHRANDT@STONYBROOK.EDU STONY BROOK UNIVERSITY
Steroid Structure http://www.raw-milk-facts.com/cholesterol_primer_T3.html http://www.britannica.com/science/steroid
Most Effective Steroids: Anabolic, Androgenic Steroids http://www.britannica.com/science/steroid
Physiological Effects of Testosterone DHT = dihydrotestosterone E2 = estradiol
Normal Testosterone Levels http://www.healthline.com/health/low-testosterone/testosterone-levels-by-age#Adolescence3
Abuse of Testosterone & Derivatives Typically dosed at 100-300 mg per week; shouldn t use more than 600 mg in a week Frequent low doses combined with exercise Routes of administration: oral, cream, i.v. Body size affects dosage in that larger body size decreases the concentration of the drug in the bloodstream
Side Effects of Testosterone Usage Men & women Aggression High blood pressure Higher levels of LDL cholesterol Liver disease Oily skin and acne Skin infections Men: Reduced sperm count Shrink testicles Enlarged breasts Women: Increased body hair Decreased breast size Deepen voice
Metabolism of Testosterone Explains Differential Side Effects Srinivas-Shankar & Wu, 2006
Non-Steroidal Muscle Growth Enhancement
Myostatin Inhibition http://muscularhypertrophysyndrome.weebly.com/introduction.html http://suppversity.blogspot.com/2011/08/doping-20-myostatin-blocker-we-are.html
Implications for Myostatin Inhibition Cohen et al., 2015
Questions? JENNIFER.SCHRANDT@STONYBROOK.EDU