Strategies Against Antimicrobial Resistance: A Public Health Priority
Addressing the rising threats of Antimicrobial Resistance (AMR) is crucial as 25,000 patients die annually due to infections caused by resistant bacteria in the EU. The costs incurred by drug-resistant infections are estimated to be 1.5 billion euros yearly. Various actions have been initiated, such as banning the use of antimicrobials for growth promotion, monitoring AMR, international collaborations, research, and the development of new antibiotics. Despite these efforts, more actions are needed to combat AMR effectively.
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EC actions against the rising threats from Antimicrobial Resistance Workshop on Antimicrobial Resistance Koen Van Dyck Head of Unit SANTE DDG2.G4: Food, Alert system and Training Directorate General Health & Food Safety (DG SANTE) European Commission 16-17 November 2015 Brussels
According to data from 2011, 25 000 patients die annually as a result of infections caused by resistant bacteria in the EU. The costs incurred by drug resistant infections amount to an estimated 1.5 billion annually, due to increases in healthcare expenditure costs and productivity losses.
AMR is a major European and global societal problem International organisations Decision-makers Scientific advice Committees CHVP CVMP ESVAC Codex Alimentarius Networks EARS-Net ESAC-Net Scientific committees SCENIHR Regulations; Directives; EC communications / decisions; Council conclusions / resolutions / recommendations Guidelines, technical reports, scientific advice, recommendations Guidelines, reports
AMR a public health priority Some actions taken so far: Ban on the use of AM for growth promotion (2006) Monitoring AMR and use of antimicrobials (EU agencies: EFSA, EMA, ECDC) International activities (TATFAR, Codex, OIE) Research Scientific opinions, data on monitoring Not enough, further action needed ! 5 5
AMR a public health priority! COM (2011) 748 17 Nov 2011 5 year action plan Holistic approach 7 key areas 12 concrete actions 6
The 12 actions Human Veterinary 1. Appropriate use 2 & 3. Appropriate use 8. International cooperation 4. Prevention of infections 5. Prevention of infections 11. Research & Innovation 6. New antibiotics 7. Need for new antibiotics 12. Communication, education 9. Surveillance 10. Surveillance 7
A. Appropriate use of antimicrobials Action n 1: Strengthen the promotion of the appropriate use of antimicrobials in human medicine in all Member States Action n 2: Strengthen the regulatory framework on veterinary medicines and on medicated feed Action n 3: Introduce recommendations for prudent use in veterinary medicine
B. Prevent microbial infections & spread Action n 4: Strengthen infection prevention and control in healthcare settings Action n 5: Adoption of a proposal for an EU Animal Health Law
C. Develop new effective AM or alternatives for treatment Action n 6: Promote unprecedented collaborative research Action n 7: Promote efforts to analyse need for new antibiotics into veterinary medicine D. Join forces with international partners Action n 8: Develop and / or strengthen multilateral and bilateral commitments for the prevention and control of AMR
E. Monitoring and surveillance Action n 9: Strengthen surveillance systems on AMR and antimicrobial consumption in human medicine Action n 10: Strengthen surveillance systems on AMR and antimicrobial consumption in animal medicine F. Additional Research and Innovation Action n 11: Reinforce and co-ordinate research efforts. Innovation. G. Communication, education and training Action n 12: Survey and comparative effectiveness research
Next steps Dedicated webpage http://ec.europa.eu/dgs/health_food-safety/amr/index_en.htm AMR progress report http://ec.europa.eu/health/antimicrobial_resistance/docs/2015_amr_progre ss_report_en.pdf AMR Roadmap http://ec.europa.eu/health/antimicrobial_resistance/docs/roadmap_amr_en. pdf Ex-post evaluation (February 2016)
Concluding remarks AMR remain a top priority for European Commission to lead at EU and work at global level Ongoing evaluation of the EC Action Plan basis to decide on the follow-up Importance of concrete actions and implementation of the action plans by all stakeholders and Member States.
