Summary of Metabolic Bone Diseases: Vitamin D Deficiency, Rickets, Osteomalacia
This summary covers metabolic bone diseases including vitamin D deficiency, rickets in children and adults, osteomalacia, hypophosphatasia, renal osteodystrophy, and osteoporosis. It discusses their manifestations, radiological findings, and key characteristics. Additionally, it touches on causes of localized osteoporosis and toxic effects on the skeleton.
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SUMMARY METABOLIC BONE DISEASES Vitamin D Deficiency Osteomalacia ) (in Children Rickets / In Adults Rickets Def. : Increase uncalcefied osteoid in immature bone. 3 Stages: 1-Active 2- Healing 3- & Healed Radiological Active manifestation : 7 1. Growth plate Wide 2. Metaphysis 3. Cortex Indistinct 4. Bone Density 5. Bone Growth 6. Ribs /Ant ends like metaphysis 7. Bone softening Bowing , Kyphoscoliosis Cupping & Fraying Deceased Retarded Delayed oss. Centers Rosary Beads 2 Healing Rickets , patient on ttt / Vit D & Ca Metaphyseal Calcification Bands 3 Healed Rickets : Absence of all manifestations - But one deformities may prolonged. By A.M.Abodahab Ass. Lecturer of Radiology - Sohag University
SUMMARY HYPO PHOSPHATASIA Vit D Resistance Rickets Autosomal recessive. Like Rickets , But when ttt with vitD Worsen Low serum Alkaline Phosphatase Mild to sever form of Rickets. Manifest as Rickets + Craniostenosis + Nephrocalcinosis OSTEOMALACIA Def: Increased uncalcefied osteoid in Mature bone. 1- MultipleLOOSER s Zones 2-Dec. Bone Density 3-Coarse faint trabeculae 4.Softening Incomplete fracture Looser zone ..multiple NB. Looser zone = Milk Man Fracture. SCURVY o Vit C deficiency Manifestation best seen at Knee joint : 1- Osteoporosis = Dec. bonedensity 2 Pencil Thin cortex epiphysis 3Provisional Zone of calcification 4- MetaphysealLucency 5 Pelkan spur Metaphyseal tibial spur 6 Sub periosteal hematoma - 6 m : 2 y Normal Scurvy 3 Periost. Reaction 4 By A.M.Abodahab Ass. Lecturer of Radiology - Sohag University
SUMMARY RENAL OSTEODYSTROPHY Renal impairment Bonedystrophy Consists of : (Osteomalacia or Rickets + osteosclerosis + 2ry Hyperparathyroidism) MANIFESTATIONs o 2ry Hyper Para Sub periosteal erosions +/- Brown tumor o Soft tissue calcifications mainly Arteries o Osteosclerosis Rugger Jersey spine o Osteomalacia Looser s Zones o In Children Rickets + Slipped capital femoral Epiphysis Sclerosis + malacia MosaicBone Superior femoralLine OSTEOPOROSIS By A.M.Abodahab Ass. Lecturer of Radiology - Sohag University
SUMMARY Causes of Localizedosteoporosis: o Immobility o Infection o Arthritis o Post Fractures o Sudeck s Atrophy : dysfunction of the sympathetic nervous system, which is involved in the regulation of blood supply to the affected part. TOXIC EFFECTS ON THE SKELETON Hyper Vit A *Sub periostealreaction +/- Pain *> 1 y age *ttt Stop vit A Lead Poisoning *Metaphys SCLEROTIC BANDS *+/- Toxic Encephalitis Vinyl Chloride * Osteolysis ofmiddle part of distalphalanx Fluorosis DIFFUSE Hyperostosis A.M.Abodahab Source : Lecture of Dr. AhmedWafei 21 Oct2017 https://www.youtube.com/watch?v=doo1tKelnTI By A.M.Abodahab Ass. Lecturer of Radiology - Sohag University
