Targeted Violence as a Risk Factor for PTSD and HIV Among Cis-GBMSM in the US
Cis-GBMSM individuals often face interpersonal violence, impacting their mental health and HIV risks. This study examines violence attribution, PTSD prevalence, and associations with serodiscordant condomless anal sex.
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Targeted violence as a risk factor for PTSD and HIV acquisition risks among cis- GBMSM in the US John Mark Wiginton, PhD, MPH, MSW; Sarah M. Murray, PhD, MSPH; Stefan D. Baral, MD, MPH, MBA; Travis D. Sanchez, DVM, MPH
Background Cisgender gay, bisexual, and other men who have sex with men (cis-GBMSM) are disproportionately exposed to interpersonal violence,1,2often motivated by sexual prejudice3,4 Such violence, regardless of motivation, carries highest conditional risk for Posttraumatic Stress Disorder (PTSD),5which also disproportionately impacts cis-GBMSM6 PTSD has been consistently linked to HIV-transmission risk behaviors among cis-GBMSM7-9 Objectives Determine prevalence of cis-GBMSM who do, do not, and are unsure about whether to attribute experiences of interpersonal violence to engagement in same-sex practices Assess prevalence of PTSD across attribution groups Test attribution-PTSD associations and PTSD-serodiscordant condomless anal sex associations
Methods American Men s Internet Survey (2020)10 Has someone ever physically hurt you (pushed, shoved, slapped, hit, kicked, choked or otherwise physically hurt you)? 13,081 began the survey 9,225 responded to a set of sexual behavior stigma items, one of which pertained to physical violence Do you believe any of these experiences of physical violence was/were related to the fact that you have sex with men? 2,886 (31.3%)
Methods (cont.) Variables Violence attribution (categorical): Unrelated (reference), related, or unsure PTSD (binary): 8-item Posttraumatic Checklist for the DSM-511 past 30 days Serodiscordant condomless anal sex with a man (binary) past year Covariates: age, race/ethnicity, sexual identity, education, HIV status, urbanicity Analysis Modified Poisson regression with robust variance estimation #1: Independent variable, violence attribution; dependent variable, PTSD #2: Independent variable, PTSD; dependent variable, serodiscordant condomless anal sex
Results Violence attribution Sample characteristics Mean age, 33.5 yrs (median, 27); 9%, teen 62%, non-Hispanic white 79%, homosexual/gay-identified; 18%, bisexual 42%, college degree or graduate education 39%, residence in large central metro area 71%, HIV-negative; 11%, HIV-positive 23%, serodiscordant condomless anal sex 23%, PTSD
Results (cont.) PTSD prevalence by attribution group Adjusted prevalence ratio with 95% confidence intervals between violence attribution and PTSD No attribution to same- sex practices (ref.) Attribution to same-sex practices Unsure 1.00 1.55 (1.34, 1.79) 1.80 (1.44, 2.25)
Results (cont.) PTSD prevalence by age group Adjusted interaction effect of binary age (15-19 years vs 20+ years) and violence attribution on PTSD No attribution to same- sex practices*age (ref.) Attribution to same-sex practices*age Unsure*age 1.00 1.49 (1.01, 2.20) 1.30 (0.77, 2.20)
Results (cont.) Age moderates the effect of violence attribution on PTSD
Results (cont.) Adjusted prevalence ratio with 95% confidence intervals between PTSD and serodiscordant condomless anal sex, confirming PTSD & HIV- transmission risk association Adjusted interaction effect of violence attribution and PTSD on serodiscordant condomless anal sex No attribution to same- sex practices*PTSD (ref.) Attribution to same-sex practices*PTSD Unsure*PTSD 1.00 No PTSD (ref.) 1.00 1.22 (0.93, 1.59) PTSD 1.22 (1.08, 1.38) 1.08 (0.71, 1.63)
Limitations Lifetime interpersonal physical violence not designated as index trauma Can be difficult to make attributions; basis not assessed Cross-sectional data; different recall periods for variables of interest Survey completed in latter 2020, well into COVID-19 pandemic Heightened mental health concerns and additional sources of PTSD/exacerbation of PTSD symptoms
Conclusions Higher PTSD risk for those who attributed violence to sexual prejudice, amplified among teens; additionally, higher risk for those unsure about attribution Improved screening to identify violence-exposed cis-GBMSM with these attribution patterns Combined PTSD/sexual risk-reduction interventions12,13 For teens, developmental tailoring; structural barriers may constrain access or impede implementation Longitudinal research to establish temporal ordering to test HIV acquisition risks via PTSD pathways
Acknowledgements MAC AIDS Fund, National Institutes of Health (R01MH110358, P30AI050409) the Emory Center for AIDS Research. Emory and Johns Hopkins research team Coauthors
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