Tennessee COVID-19 Surveillance Update: Cases Plateaued, Hospitalizations Rising
"Latest update on COVID-19 surveillance in Tennessee as of 02 Dec 2021. Case counts have leveled off, with less than 1000 cases per day reported in the last week. Hospitalizations are increasing, currently at 849 adult hospitalizations. PCR test positivity is on the rise at around 8.6%. Stay informed with the most recent data."
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Presentation Transcript
Magdalena Dorvil-Joanem, MD, MPH COVID-19 Surveillance TN Dept of Health
COVID-19 Surveillance Summary: 02 Dec 2021 Cases counts have plateaued. <1000per day in the last week COVID-19 hospitalizations increasing. 849 currently; 718 last week. The PCR percent positivity is rising. ~8.6%currently; ~6.8% last week. Testing volumedecreased. Omicronvariant.
Case Counts(Weekly) By Specimen CollectionDate 1,318,572 TotalCases
Current COVID Hospitalizations 849 adult hospitalizations
Current COVID Pediatric Hospitalizations 11 pediatric hospitalizations
COVID-19 Testing by Week Total PCR & Antigen Tests(Thousands) by Week 400 350 300 250 200 150 71k 100 52k 50 0 2020 2021
PCR TestPercent Positivity 60.00% 12/02:8.6% 50.00% 7-dayaverage 11/28: 8.81% 40.00% PercentPositive 30.00% 20.00% 10.00% 0.00%
Tennessee DataOnline www.tn.gov/health/cedep/ncov
SARS-CoV-2 B.1.1.529 (Omicron) Variant Lab in Botswana isolated B.1.1.529 in samples collected on 11/11 11/23Botswana was first lab to upload sequence to GISAID Hong Kong also uploaded this sequence very close to the same time After a period of substantial decline, South Africa saw a rapid increase in case rates, increasing to over 20% 11/14first case in SouthAfrica reported 11/26 WHO named Omicronthe 5thSARS-CoV-2 variant of concern
Map of Confirmed Cases of B.1.1.529 Variant Courtesy of BNO News: https://newsnodes.com/nu_tracker
1stOmicron Variant Case in U.S. 01 DEC 2021 San Francisco Health Department reported case to CDC on 12/01 Fully vaccinated person traveled from South Africa on 11/22 Developed mild symptoms, self-isolated, notified all contacts, and sought testing CDC confirmed genomic sequence from UCSF lab of the PCR positive specimen from the person is B.1.1.529 (Omicron) Case has fullyrecovered Allcontacts tested negative and are quarantined Second case confirmed on 12/02 in Minnesota Fully Vaccinated adult male who received booster shot in early November and did NOT travelinternationally, but attended convention in NYC Case developed only mild symptoms
OmicronMutations S-gene target failure PCR proxyfor new variant was noted in specimenfrom South Africa B.1.1.529 lineageidentifiedwhen specimen was sequenced Has substantial increase in mutations (about 50 amino acid changes, >30 of these mutationsare on the spikeprotein) May have increasedtransmissibilityand immune evasion(NO DATAyet) Implicationsfor SARS-CoV-2 genomicsurveillance Expectthe CDC rt-RTPCR assays to detectOmicron AnticipateSGTF if usingTaqPath COVID-19 Combo kit If potentialOmicron variantdetected,confirm via genomicsequencing CDC is revisingguidance for Enhanced Surveillance ES21-01 (SGTF) plans to reopen to target potential Omicron next week ES21-03 Additional Mutations accepting submissions of previously sequenced specimen resembling Omicron
Summary of What We Know WeKnow Virus infected fully vaccinated persons, person who had received a booster, and people who have recovered from infection with delta variant Infected individuals in South Africa have been predominantly young adults Virus has large amounts of mutations, >30 of which are on the spike protein, may be clue on transmissibility. Not enough info to determine yet WeDO NOTKnow Transmissibility Vaccine effectiveness Disease severity
National Estimates of SARS-CoV-2 Lineages Delta estimated at 99.9% B.1.617.2 majorvariant AY .1 and AY .2 Retrieved from CDC COVID Data Tracker: https://covid.cdc.gov/covid-data- tracker/#variant-proportions
How to Fight Omicron Get vaccinated Get boosted Followpreventative measures Use masks Avoid crowds and poorly ventilated spaces Physicaldistance Hand hygiene Quarantine/Isolate if appropriate
