The Trisynaptic Neuronal Network of the Hippocampus

The Trisynaptic Neuronal Network of the Hippocampus
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The hippocampus, a vital part of the limbic system, is responsible for memory and spatial navigation. Learn about its structure, including the dentate gyrus and subicular complex, and explore the trisynaptic circuit that defines its neuronal pathways. Delve into the intricacies of the hippocampal anatomy and understand the significance of the trisynaptic loop in cognitive functions.

  • Hippocampus
  • Neuronal Network
  • Memory
  • Spatial Navigation
  • Trisynaptic Circuit

Uploaded on Mar 05, 2025 | 0 Views


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  1. The Trisynaptic Neuronal Network Of The Hippocampus. Created By: Alex Szendrei

  2. The Hippocampus Part of the limbic system Memory and spatial navigation Located in the medial temporal lobe, underneath the cortical surface Two halves: left and right sides of the brain Resembles a seahorse, "hippo- kampos"

  3. Parts Of Hippocampus Dentate gyrus (DG) Hippocampus proper: CA1 3 (cornu ammonis) Subicular complex: Subiculum (sb) Presubiculum (prs) Parasubiculum (pas) Entorhinal cortex (EC): Medial (MEC) Lateral (LEC)

  4. Trisynaptic Circuit In transverse plane, three interconnected afferent pathways Three major cell groups: granule cells, CA3 pyramidal neurons, and CA1 pyramidal cells. Trisynaptic pathway Entorhinal cortex -> the dentate gyrus Dentate gyrus -> CA3 via mossy cell fibers. Ca3 -> ca1 via schaffer collaterals Ca1 -> sbiculum, carried out through the fornix. Collectively the dentate gyrus, ca1 and ca3 of the hippocampus compose the trisynaptic loop.

  5. Thank you for your attention. Sources: Http://www.News-medical.Net/health/hippocampus-what-is-the-hippocampus.Aspx Http://neuralnetoff.Umn.Edu/mediawiki/index.Php/hippocampal_anatomy Http://www.Nature.Com/nrn/journal/v9/n1/fig_tab/nrn2303_f1.Html Https://en.Wikipedia.Org/wiki/trisynaptic_circuit Http://www.Scholarpedia.Org/article/entorhinal_cortex Https://www.Ncbi.Nlm.Nih.Gov/pmc/articles/PMC2492885/ Http://neuroscience.Uth.Tmc.Edu/s4/chapter05.Html Https://www.Cs.Cmu.Edu/afs/cs/academic/class/15883-f13/slides/hc-anatomy.Pdf

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