Triglyceride Synthesis and Significance
Explore the conditions favoring triglyceride synthesis, the activation of fatty acids, and the biomedical and clinical significance of triglycerides. Learn how factors such as diet, insulin, and metabolic intermediates play a crucial role in lipid metabolism.
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Presentation Transcript
CONDITIONS THAT FAVOUR SYNTHESIS OF TGS Increased diet of Carbohydrates and protein High intake of Glucose in diet. Insulin stimulate TGs synthesis in adipose tissues.
2. ACTIVATION OF FREE FATTY ACID TO FATTY ACYL Co A
BIOMEDICAL SIGNIFICANCE OF TGs Insulin stimulates TGs synthesis in adipose tissues by enhancing glucose transport in adepocytes. DHAP, an intermediate metabolite in glycolysis and glycerol-3-P connect the Carbohydrates and lipid metabolism. 1,2-DAGP and DAG is intermediates of TGs synthesis. They can also be utilize for synthesis of Glycerophospholipids.
CLINICAL SIGNIFICANCE OF TRIGLYCERIDES
