Understanding Barbiturates, Thiopental, and Ketamine: An Overview
Explore the characteristics and uses of barbiturates such as phenobarbital, chemobarbital, and pentobarbital based on their duration of action. Learn about the properties of Thiopental sodium, its administration, and effects, including apnea and hypotension. Discover the features of Ketamine hydrochloride, its dosages for different animals, onset, duration, and effects, including increased heart rate and blood pressure. Dive into the world of anesthesia with these potent substances.
Uploaded on | 0 Views
Download Presentation
Please find below an Image/Link to download the presentation.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author. If you encounter any issues during the download, it is possible that the publisher has removed the file from their server.
You are allowed to download the files provided on this website for personal or commercial use, subject to the condition that they are used lawfully. All files are the property of their respective owners.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author.
E N D
Presentation Transcript
Barbiturates Long act: 8-12 hours (phenobarbital) Intermediate act: 2-6 hours (chemobarbital) Short act: 1-2 hours (pentobarbital) Ultra short act: 10-15 minutes (thiopental)
Thiopental sodium Alkaline, solution 2.5-5 %, apnea, Onset: 30 sec. hypotension, good relaxation, dose 5-10 mg/kg, 1/3 injected rapidly then to effect, Solution is ineffective after 1 week High protein binding Prolong recovery after infusion
Ketamine hydrochloride No good relaxation, nystagmous Some reflexes remain active (palpebral) Very safe, could be injected IM Increase in HR and BP Dose in horse: 2.2 mg/kg Dose in small animals: 5-20 mg/kg Onset: 1 min, Duration: 10-15 min Good anesthesia with xylazine
