Understanding Mature Cystic Teratoma of the Ovary
Explore the features, risks, and histology of mature cystic teratoma of the ovary. Learn about its composition, potential for malignant transformation, and tissue origins. See images and microscopic features to enhance your understanding.
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Presentation Transcript
Mature cystic teratoma, Ovary Tin Tin Thein, Aye Aye Wynn, Siti Zaleha, Lia Natasha Pathobiology and Medical Diagnostic Department FPSK, UMS 5/2/2025 1
Mature cystic teratoma, Gross specimen 5/2/2025 2
Mature cystic teratoma . cut section of ovary. It is bulky, smooth external surface and solid in nature. . The wall is slightly thick and lined by an opaque, gray-white, wrinkled epidermis. . Protruding of hair shafts and cheesy material. [sometimes bone, calcification, areas of necrosis & haemorrhage can be seen] Important risk are 1. About 1% the dermoids undergo malignant transformation. (Squamous cell carcinoma, thyroid ca, melanoma) 2. Subsequent extraovarian spread (proportion of tissue containing immature neuroepithelium) 5/2/2025 3
Mature cystic teratoma, Microscopic feature Keratin Sebaceous gld Epidermis Ganglion 5/2/2025 4
Histology . cyst walls is composed of stratified squamous epithelium with underlying sebaceous glands, hair shafts, other skin adnexal structures. . Tissues from other germ layers can be identified: Cartilage, bone, thyroid and neural tissue Ectodermal derivative: Skin & skin appendage components Mesodermal : cartilage & smooth muscle Endodermal: respiratory and gut epithelium 5/2/2025 5
