Understanding Protein-Protein Interactions on Biosensor Surfaces
Learn how to use COMSOL Multiphysics 5.1 to model reaction kinetics and surface binding in protein-protein interactions on biosensor surfaces. Explore the creation of 2D models, understanding varying concentrations of reacting species, and future goals of obtaining experimental data for biotin-streptavidin binding. All information is sourced from COMSOL Multiphysics 5.1 Transport and Adsorption.
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Presentation Transcript
Understanding Protein- Protein Interactions on Biosensor Surfaces Vincent Chang Mentor: Lisa Plucinski
Overview Learn how to use the COMSOL application Use COMSOL models to understand the fundamentals of reaction kinetics and surface binding
Program Used COMSOL Multiphysics 5.1 Transport and Adsorption Modeling phenomena of surface binding in different dimensions (3D to 2D).
Progress Creating a 2D model that displays the concentration of the reacting species at various areas of the surface through time Understanding the physics behind why surface concentration of reacting species vary through position and time Understanding reaction rates on surface binding through time
Future Goals Obtain experimental data for biotin-streptavidin binding on a biosensor with a microfluidic channel Explore how various experimental parameters impact protein-binding kinetics Explore methods to fit experimental data to models
Sources All information is received through COMSOL Multiphysics 5.1 Transport and Adsorption
