WHO DALY Calculations and GBD 2010 Disability Weights Overview

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This article provides insights into WHO DALY calculations, GBD 1990 and GBD 2010 disability weights, and problems associated with disability weight assignments. It covers topics such as YLL, age-weighted standards, and revisions to disability weights by WHO. Explore the complexities of defining disability weights from various health conditions and their impact on health statistics and informatics.

  • WHO
  • DALY
  • GBD 2010
  • Disability Weights
  • Health Statistics

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  1. WHO DALY calculations Colin Mathers Coordinator, Mortality and Health Analysis Unit World Health Organization, Geneva Burden of disease methodological workshop Royal Society of Edinburgh, 15-16 September 2016 Health Statistics and Informatics

  2. Standard loss function for YLL GBD 1990 age- weighted, discounted Male 33.27 34.22 35.17 37.22 37.31 36.02 33.84 31.11 28.08 24.91 21.74 18.63 15.65 12.82 10.19 7.80 5.71 4.00 2.68 1.37 GBD 1990 no age- weights or discounting Male 79.94 78.85 77.77 72.89 67.91 62.93 57.95 52.99 48.04 43.10 38.20 33.38 28.66 24.07 19.65 15.54 11.87 8.81 6.34 3.82 GBD 2010 WHO GHE Age Female 33.38 34.34 35.29 37.36 37.47 36.22 34.08 31.39 28.40 25.30 22.19 19.16 16.26 13.52 10.96 8.60 6.45 4.59 3.09 1.23 Female Persons Persons 82.43 86.01 81.36 85.68 80.28 83.63 75.47 78.76 70.51 73.79 65.55 68.83 60.63 63.88 55.72 58.94 50.83 54.00 45.96 49.09 41.13 44.23 36.36 39.43 31.68 34.72 27.10 30.10 22.64 25.55 18.32 21.12 14.24 16.78 10.59 12.85 7.56 9.34 3.59 5.05 0 91.93 91.55 89.41 84.52 79.53 74.54 69.57 64.60 59.63 54.67 49.73 44.81 39.92 35.07 30.25 25.49 20.77 16.43 12.51 7.60 1 month 1 5 10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85+ Health Statistics and Information Systems

  3. Health Statistics and Informatics

  4. GBD2010 disability weights Health Statistics and Information Systems

  5. GBD2010 disability weights 0.126 IQ<35 Health Statistics and Information Systems

  6. Problems with GBD 2010 disability weights Amputation of both arms with treatment (0.044) less severe than amputation of one arm with treatment (0.13) Urinary incontinence (0.142) more severe than treated paraplegia (0.047), which usually involves incontinence also Complete hearing loss (0.033) of similar severity to mild anxiety disorder (0.030) or mild neck pain (0.040) Mild intellectual disability, IQ 50-69 (0.031) of similar severity to viral warts (0.030) Severe intellectual disability , IQ 20-34 (0.126) lower in severity than urinary incontinence (0.142) Heroin dependence (0.64) more severe than cancer terminal phase (0.51) Health Statistics and Information Systems

  7. WHO Revisions to Disability Weights 1. Dutch disability weights study (Stouthard et al 1997,200) gave EQ5D+ descriptions for health state sequelae 2. Expanded set of EQ5D+ descriptions for GBD2010 health states 3. Regression prediction model fitted to GBD2010 DW and EQ5D+ health states 4. Used to estimate revised DW for outlier DW for infertility, intellectual disability, hearing loss, vision loss, amputation, disfigurement 5. Masked DW used for drug and alcohol dependence states 6. GBD 2013 also revised many of these weights using revised lay descriptions in European surveys Health Statistics and Information Systems

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