Clinical Research Grants for Physician Scientists

DACCPM CLINICAL RESEARCH GRANTS ARC Applied Research Didactic July 7, 2021

Grant Program Research activities are an integral aspect of the departments mission To support these activities, the DACCPM provides funding of up to 100K in direct costs annually for early and mid-career physician scientists for the conduct of their clinical research studies The goal of these grant mechanisms is to: 1. stimulate clinical research in the DACCPM 2. aid in the development of projects that may ultimately receive extramural funding for investigators who aim to transition to independence We are pleased to announce two new internal grant funding opportunities: Clinical Seed Grants (CSG) and Clinical Project Grants (CPG)

Clinical Research Grants CLINICAL SEED GRANT 5K Grant Up to 10 Clinical Seed Grants will be awarded each year, with emphasis on funding applications across all clinical divisions. CLINICAL PROJECT GRANT 25K Grant Up to 2 Clinical Project Grants will be awarded each year. It is our aim to fund at least one in each division

Grant Specifics | Eligibility Eligibility The applicant must meet all of the following eligibility requirements: CRNAs or faculty members (MD or PhD) who hold HMS appointment of Instructor, Assistant Professor or Associate Professor Active member of the MGH DACCPM throughout the duration of the award Additional Requirements for the Clinical Project Grant: Demonstrated track record of academic research Other Info Faculty members who currently hold or who have previously held extramural grants (excluding NIH R01 and K grants) will be eligible to apply, but priority will be given to applicants without funding. The DACCPM research grants are not intended for established investigators who are changing areas of interest. Only applications for clinical research projects will be accepted. These grant mechanisms are not intended to support basic science or bench research.

Grant Specifics | Finances Financial Info Clinical Seed Grants are limited to a maximum of $5,000 and the Clinical Project Grant to $25,000 in direct costs, however appropriate funds should be requested based on the research needs. The funding can be used to cover research expenses such as supplies, study-related patient care costs (ex. study medications), equipment and remunerations. Awards are not intended to support salaries or to buy non-clinical time. Funds can be allocated for external consultants or services however, provided there is no internal expertise available for the proposed project. Indirect costs should not be included in the submitted budget template. All funds must be expensed by the end of the funding period unless permission is granted. A no-cost extension of up to 12 months may be requested, if justification for the extension is provided and approved. A maximum of one no-cost exception will be allowed. Recipients of the Clinical Project Grant award who later receive significant (R01 or equivalent) additional extramural funding for the same project during the award period will be expected to relinquish this award.

Grant Specifics | Application Attachment Description Page Limit(s) Applications Investigators are permitted to submit one application each year in each of the grant categories. Project Summary / Abstract A succinct and accurate description of the proposed work. 250 words The research strategy should discuss the specific aims of the research, the background and significance, the study approach and methods, as well as the study timeline. For the Project grant, plans for a related grant submission should be delineated, as well as how the proposed project fits into the PI s career goals. Please provide a brief but detailed list of budgeted items in accordance with the financial information above. Only direct costs should be included in the submitted budget. No salary support is provided. A narrative explanation of each of the components of the budget, which justifies the cost in terms of the proposed work. The explanations should focus on how each budget item is required to achieve the aims of the project and how the estimated costs in the budget were calculated. Please be sure to discuss roles and relevant experience of all personnel involved, as well as any collaborators or outside laboratories, if applicable. The PI s biosketch, in the NIH format, is required for submission. Additional biosketches may be submitted for key study personnel such as research mentors, co-investigators collaborators, as appropriate in relation to the research project. References should be cited in AMA style and referenced in the sequence they appear in the text. Seed Grant: 2 pg Research Strategy Project Grant: 5 pg Budget ARC Template If an applicant submits both a Clinical Seed and Project Grant they may not be for the same project, and only one will be funded. Seed Grant: 1 pg Budget Justification Project Grant: 2 pg Biosketch Max of 5 pages References N/A

Grant Specifics | Review & Awards Grant Review Grant applications will be peer-reviewed by members of the Department s Clinical Research Study Section. The reviewers may ask for comments from someone outside the committee, if necessary. The final funding decision will be made in consultation with the Anesthesia Research Center and if needed, the Vice Chair for Research and/or Anesthetist-in-Chief. A formal report of the grant review will be sent to all applicants. Awards Awards are limited to one grant per faculty member per year. JIT: The grant/protocol must have approval from the Mass General Brigham Institutional Review Board (IRB) before the project can be funded.

Important Deadlines Online Application Opens July 1, 2021 Applications Due August 31, 2021 5:00 PM Merit Review by Clinical Research Study Section September 30, 2021 Applicant Award Notification October 2021 Departmental Notification DACCPM Clinical Research Night Project Period Begins (Pending IRB Approval) January 1, 2022

Application Deadline: August 31st, 2021 5:00 PM EST Please visit the ARC website for more information on eligibility and to apply: www.mghanesthesiaresearch.com/grants

Anesthesia Research Center Given its commitment to supporting clinical research in the department, services and effort from the Anesthesia Research Center (ARC) will be made available to successful applicants to supplement the clinical research awards. This includes effort from ARC statisticians, data scientists, and clinical research coordinators, as needed, for the conduct of the proposed project. Investigators who hope to receive support from ARC in any capacity (effort, data queries, space / equipment, etc.) must contact ARC prior to grant submission for approval. ARC will function like a NIH Program Officer for these grants, so feel free to contact us as you draft your grant application

Questions DACCPM CLINICAL RESEARCH GRANTS Resources www.mghanesthesiaresearch.com/grants almueller@mgh.harvard.edu (617-726-9252)