Epilepsy: Diagnosis and Neurotransmitters
Dr. Hardeep Singh Malhotra MD, DM, FIACM, MNAMS, an Associate Professor at King George's Medical University, presents a series of Multiple Choice Questions (MCQs) focusing on the diagnosis of epilepsy, excitatory neurotransmitters, and genetic abnormalities associated with various types of epilepsy syndromes. Explore the link between seizures and familial history, as well as the role of sodium, calcium, potassium, and chloride channel mutations in different types of epilepsy. Enhance your knowledge on epilepsy through these insightful questions.
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Presentation Transcript
Epilepsy Dr. Hardeep Singh Malhotra MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology, King George s Medical University, Lucknow
MCQ-1 When do you label a seizure as epilepsy ? Presence of family history >1 unprovoked seizure >1 provoked seizure >2 provoked seizures
MCQ-1 When do you label a seizure as epilepsy ? Presence of family history >1 unprovoked seizure >1 provoked seizure >2 provoked seizures
MCQ-2 All of the following are excitatory neurotransmitters except: AMPA NMDA GABA Glutamate
MCQ-2 All of the following are excitatory neurotransmitters except: AMPA NMDA GABA Glutamate
MCQ-3 Which of the following abnormality is associated with Generalized Epilepsy & Febrile Seizures plus syndrome? Sodium channel mutations Calcium channel mutations Potassium channel mutations Chloride channel mutations
MCQ-3 Which of the following abnormality is associated with Generalized Epilepsy & Febrile Seizures plus syndrome? Sodium channel mutations Calcium channel mutations Potassium channel mutations Chloride channel mutations
MCQ-4 Which of the following abnormality is associated with Juvenile Myoclonic Epilepsy ? Sodium channel mutations Calcium channel mutations Potassium channel mutations Chloride channel mutations
MCQ-4 Which of the following abnormality is associated with Juvenile Myoclonic Epilepsy ? Sodium channel mutations Calcium channel mutations Potassium channel mutations Chloride channel mutations
MCQ-5 Which of the following abnormality is associated with Temporal lobe epilepsy ? Sodium channel mutations Calcium channel mutations Potassium channel mutations Chloride channel mutations
MCQ-5 Which of the following abnormality is associated with Temporal lobe epilepsy ? Sodium channel mutations Calcium channel mutations Potassium channel mutations Chloride channel mutations
MCQ-6 Pathophysiologically, which is the most important reason for the precipitation of seizure? Increased Glutamate, increased GABA Increased AMPA, increased GABA Increased Glutamate, decreased GABA Decreased Glutamate, increased GABA
MCQ-6 Pathophysiologically, which is the most important reason for the precipitation of seizure? Increased Glutamate, increased GABA Increased AMPA, increased GABA Increased Glutamate, decreased GABA Decreased Glutamate, increased GABA
MCQ-7 Clinically, the most relevant epilepsy classification system is: ILAE 1985 ILAE 1989 ILAE 1991 ILAE 2006
MCQ-7 Clinically, the most relevant epilepsy classification system is: ILAE 1985 ILAE 1989 ILAE 1991 ILAE 2006
MCQ-8 Which of the following is not a localization- related epilepsy? Benign childhood epilepsy with centrotemporal spikes Juvenile myoclonic epilepsy Childhood epilepsy with occipital paroxysms Primary reading epilepsy
MCQ-8 Which of the following is not a localization- related epilepsy? Benign childhood epilepsy with centrotemporal spikes Juvenile myoclonic epilepsy Childhood epilepsy with occipital paroxysms Primary reading epilepsy
MCQ-9 Which of the following is not an idiopathic generalized epilepsy? Juvenile absence epilepsy Epilepsy with grand mal seizures on awakening Childhood absence epilepsy Lennox-Gastaut syndrome
MCQ-9 Which of the following is not an idiopathic generalized epilepsy? Juvenile absence epilepsy Epilepsy with grand mal seizures on awakening Childhood absence epilepsy Lennox-Gastaut syndrome
MCQ-10 Which is the most important differential diagnosis of first seizure ? Migraine without aura Abdominal migraine Syncope Migraine with aura
MCQ-10 Which is the most important differential diagnosis of first seizure ? Migraine without aura Abdominal migraine Syncope Migraine with aura