Exploring Biomedical Radiotracer Diffusion in Target Chamber
"Investigate the diffusion and effusion processes of biomedical radiotracers in the SPES-ISOLPHARM target chamber through simulations and theoretical studies. Explore isotope generation, release, and production in SiC targets with computational modeling. Analyze parameters affecting atom release time, isotope production, and diffusion in solid surfaces."
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Presentation Transcript
Laboratori Nazionali di Legnaro INFN Diffusion and effusion of biomedical radiotracers in the SPES-ISOLPHARM target Sara Luise May 19th, 2025 1
Simulation of isotope generation and release process Theoretical study of the diffusion and effusion processes of magnesium (Mg-28) isotope in silicon carbide (SiC) targets Computational modelling with Geant4 Monte Carlo software (release 10.7) Investigate the key parameters of the system quantify the average release time of the atoms produced 2
Isotope production 7 disk-shape targets spaced to dissipate the energy deposited material: SiC SA (no pores) 40 MeV proton beam T = 1600 c Changed simulation geometry: Target material Disk radius Thickness of the disks Positions of the disks o o o o 3
Diffusion and effusion Effusion in the target chamber: Diffusion in the molecules of the target material: nuclide reaches the target surface and travels in the vacuum system until it reaches another solid surface average sticking-time summed to the particle global time average time spent by a particle to exit the grain calculated with the solution of Fick s equation for a sphere/cilinder Changed simulation parameters: o Target temperature o Distribution of molecule radius o Diffusion coefficient for Mg in SiC o Avarage sticking time of Mg in Ta and C 4
